Sequelae after laryngeal cancer surgery

After suffering from laryngeal cancer, patients will be very worried. Usually patients will choose surgery for treatment. So what are the sequelae of radiotherapy after laryngeal cancer surgery? What should we pay attention to in daily life? What are the adverse reactions of radiotherapy after laryngeal cancer surgery?

Systemic reactions: including fatigue, dizziness, loss of appetite, nausea, vomiting, tastelessness or change in taste in the mouth, insomnia or drowsiness, etc. Some patients may experience changes in blood count, especially leukopenia. Although the degree varies, it can generally be overcome through symptomatic treatment and radiotherapy can be completed. If necessary, vitamin B1, B6, C, metoclopramide, etc. can be taken. If the white blood cell count drops below 3×109, radiotherapy should be suspended.

Local reactions: including reactions of the skin, mucous membranes, and salivary glands. Skin reactions manifest as dry dermatitis or even wet dermatitis. Anti-inflammatory ointments with 0.1% borneol talc or lanolin as the base can be used topically. Mucosal reactions manifest as congestion, edema, exudation, and accumulation of secretions in the nasopharyngeal and oropharyngeal mucosa. Gargles and lubricating anti-inflammatory agents can be used topically. In a small number of patients, parotid swelling may occur after 2Gy of parotid irradiation, and the swelling gradually subsides in 2 to 3 days. When irradiated with 40GY, saliva secretion is significantly reduced, while oral mucosal secretion increases, and the mucosa becomes congested and swollen. Patients have dry mouth and difficulty eating dry food. Therefore, excessive irradiation of the parotid gland should be avoided.

Sequelae of radiotherapy: mainly temporomandibular joint dysfunction, soft tissue atrophy and fibrosis, radiation-induced dental caries, radiation-induced osteomyelitis of the jaw bone, and radiation-induced encephalomyelopathy.