Understand the 3 special types of ovarian cancer

Ovarian cancer is extremely harmful to women's physical and mental health. There are various types of ovarian cancer, and the treatment methods for different types of ovarian cancer are also different. The pathogenesis of ovarian cancer is complex and the disease is changeable. Ovarian cancer can be divided into many types based on its pathogenesis. Some of them are high-risk factors for ovarian cancer, and patients need to pay more attention.

1. Sporadic ovarian cancer

Sporadic ovarian cancer has obvious gene mutation. Currently, two recently developed methods for detecting gene mutations, namely denaturing high performance liquid chromatography (DHPLC) and fluorescent dideoxy fingerprinting (f-ddF), are used to detect heterogeneous tumor specimens to confirm the gene mutation results of sporadic ovarian cancer. Classification of ovarian cancer: Sporadic ovarian cancer generally occurs in the second generation of blood relatives in the family, including brothers and sisters, children and their grandparents on both sides.

2. Familial ovarian cancer

Familial ovarian cancer refers to a family with two or more first- or second-generation blood relatives who suffer from ovarian cancer. The disease is often passed down through the family. Women in such families have a high chance of developing ovarian cancer. Women without a family history of ovarian cancer have a lifetime risk of 1/70. If one first-degree relative is sick, the risk increases to 5%; if two first-degree relatives are sick, the risk is 7%. Therefore, screening, diagnosis, consultation and preventive treatment for them are one of the important issues in the field of gynecological tumors. Other gynecological tumors such as breast cancer and endometrial cancer may also follow this familial tumor formation pattern.

3. Hereditary ovarian cancer

There are certain genetic factors in the occurrence of ovarian cancer. Women with a family history of ovarian cancer are much more likely to develop the disease than those without a family history. It is mainly manifested as a clustered ovarian cancer family with autosomal dominant inheritance. Patients with hereditary ovarian cancer develop at an early age, with an average age of about 52 years old, about 7 years earlier than ordinary ovarian cancer patients. Patients with this type of obvious hereditary disease should pay more attention and strive for early diagnosis to obtain the best therapeutic effect.