Symptoms of lower limb muscle atrophy

The older the human body is, the more susceptible it is to various diseases. As people gradually age, their internal organs begin to fail, and eventually their metabolism slows down. Various diseases continue to occur, and the limbs of the body are also prone to diseases. For example, limb muscle atrophy may cause people to be unable to walk normally. So what are the symptoms of lower limb muscle atrophy?

1. Symptoms of calf muscle atrophy

1. Neurogenic muscular atrophy: caused by lower motor neurons and their damage. When the anterior horn cells and brainstem motor nerve nuclei are damaged, muscle atrophy is distributed segmentally, more common in the distal limbs, and is symmetrical or asymmetrical, without sensory impairment. Fasciac tremors often occur, and the degree of muscle strength and tendon reflexes is related to the degree of damage.

2. Myogenic atrophy: caused by diseases of the muscles themselves. Atrophy is not distributed according to nerves, and is often proximal, with symmetrical muscle atrophy of the pelvic girdle and shoulder girdle, and in a few cases distal. Accompanied by muscle weakness, without muscle fiber tremor and sensory disturbance. Serum creatine phosphokinase, lactate dehydrogenase, aspartate aminotransferase, phosphoglucomutase, aldolase, etc. were all elevated to varying degrees, with creatine phosphokinase being the most sensitive. The characteristic change of electromyography is the appearance of short-duration multiphasic potentials.

3. Others: Central muscular atrophy is generally accompanied by hyperreflexia or pathological reflexes. Ischemic muscular atrophy is mostly caused by muscle ischemia and aseptic necrosis due to various arteritis, thrombosis, etc. Disuse muscle atrophy is related to long-term lack of exercise. And most of them are reversible.

2. Clinical symptoms of leg muscle atrophy

1. Myogenic leg muscle atrophy: Muscular dystrophy is a common symptom, including malnutrition myotonia, polymyositis trauma such as crush syndrome, periodic paralysis, ischemic myopathy, metabolic myopathy, endocrine myopathy, gluttonous myopathy, and neuromuscular transmission disorders such as myasthenia gravis.

2. Neurogenic leg muscle atrophy

Atrophy: Mainly lower motor neuron and spinal cord lesions, causing vertebral bone hyperplasia, intervertebral disc lesions, spinal nerve tumors, arachnoiditis, neuritis, plexus, spinal nerve tumors, arachnoiditis, neuritis, plexus lesions, nerve damage, syringomyelia, motor neuron disease Guillain-Barré syndrome, disuse muscular atrophy caused by spinal cord lesions and brain lesions, etc.

1. Disuse leg muscle atrophy: Upper motor neuron disease is caused by long-term muscle inactivity, which leads to systemic wasting diseases such as malignant tumors, hyperthyroidism, poliomyelitis, autoimmune diseases, etc. The patient's long-term reduction in exercise leads to muscle atrophy.