What is the therapeutic effect of potassium chloride injection?

Potassium chloride injection is a relatively common therapeutic drug, especially in the treatment of hypokalemia. We know that once hypokalemia occurs in a person, it is very harmful to the human body. At this time, potassium chloride injection can be used for treatment, which can effectively prevent the symptoms of hypokalemia. In addition, if poisoning from drugs such as digitalis occurs, potassium chloride injection can also be used for treatment.

1. Treatment of hypokalemia

Treatment of hypokalemia caused by various reasons, such as insufficient food intake, vomiting, severe diarrhea, use of potassium-excreting diuretics, hypokalemic familial periodic paralysis, hypokalemia caused by long-term use of glucocorticoids and supplementation of hypertonic glucose, etc.

2. Prevent hypokalemia

To prevent hypokalemia, preventive potassium supplementation is required when the patient has potassium loss, especially if hypokalemia is harmful to the patient (such as patients using digitalis drugs), such as eating very little, severe or chronic diarrhea, long-term use of corticosteroids, potassium-losing nephropathy, Bartter syndrome, etc.

3. Digitalis poisoning

Digitalis poisoning causes frequent, multifocal premature beats or tachyarrhythmias.

Used for patients with severe hypokalemia or those who cannot take oral medication. The general usage is to add 10-15 ml of 10% potassium chloride injection to 500 ml of 5% glucose injection and drip (avoid direct intravenous drip and push injection). The dose, concentration and speed of potassium supplementation are determined based on the clinical condition, blood potassium concentration and improvement of the potassium deficiency pattern on the electrocardiogram. The potassium concentration should not exceed 3.4g/L (45mmol/L), the potassium supplementation rate should not exceed 0.75g/hour (10mmol/hour), and the daily potassium supplementation amount should be 3-4.5g (40-60mmol). When potassium deficiency in the body causes severe rapid ventricular ectopic arrhythmias, such as torsades de pointes, short bursts, recurrent multiline ventricular tachycardia, ventricular flutter and other life-threatening severe arrhythmias, the potassium salt concentration should be high.