Sinusitis is a disease problem that affects many people, and it is necessary to focus on correct and scientific treatment. The causes of sinusitis include genetic factors. If there is a family history of these diseases, the probability of family members suffering from these diseases will increase. People with susceptible nasal mucosa are also prone to sinusitis. 1. Genetic factors: People with a family history of allergies are more likely to develop this disease. The patients' families often have a history of asthma, urticaria or drug allergy. In the past, such patients were called atopic individuals, whose ability to produce IgE antibodies was higher than that of normal people. However, in recent years, some authors have found that there is no significant difference in the incidence rate between twins and the general population. 2. Susceptibility of nasal mucosa Susceptibility arises from the frequent stimulation of antigenic substances, but the degree of susceptibility depends on the number of mast cells and alkaliphils in the nasal mucosal tissue and the ability to release chemical mediators. It has been confirmed that the number of the above-mentioned cells in the nasal mucosa of patients with allergic rhinitis is not only higher than that of normal people, but also has a stronger ability to release chemical mediators. 3. Antigen substances that stimulate the body to produce IgE antibodies are called allergens. When the allergen enters the nasal mucosa again, it combines with the corresponding IgE and causes an allergic reaction. |
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