Treatment of chronic arsenic poisoning

Patients with chronic arsenic poisoning must pay attention to correct improvement. First of all, timely treatment measures should be taken for some arsenic poisoning symptoms. Chronic arsenic poisoning can be treated with 10% sodium thiosulfate, injected intravenously to assist renal excretion, and attention should be paid to preventing acute renal failure.

1. In case of accidental oral poisoning, the stomach should be lavaged with warm water, saline or 1% sodium bicarbonate as soon as possible, followed by injection of 30g of activated carbon, 20-40g of magnesium oxide or protein water. Freshly prepared ferric hydroxide can also be taken orally immediately to form insoluble ferric arsenate with arsenic, and then sodium sulfate can be given as a catharsis.

2. There are specific antidotes for acute arsenic poisoning. Sodium disodium sulfoxide and disodium butyl sulfoxide have good arsenic-removing effects. Penicillamine also has a certain arsenic-removing effect and should be used as soon as possible (the dosage and method of use need to follow the doctor's instructions). Pay attention to preventing, treating and correcting dehydration, shock and electrolyte imbalance. Severely ill patients should be given hemodialysis as soon as possible. Hemodialysis can effectively remove arsenic from the blood and prevent and treat acute renal failure.

3. Chronic arsenic poisoning can be treated with 10% sodium thiosulfate injected intravenously to assist renal excretion. Skin or mucous membrane lesions can be applied externally with 2.5% diisopropyl alcohol ointment or dexamethasone ointment. When delayed polyneuropathy occurs, symptomatic treatment is given.

4. Symptomatic and supportive treatment: For severe abdominal pain, intramuscular injection of atropine or pethidine can be used; for muscle spasm pain, calcium gluconate can be slowly injected intravenously. Supplement vitamin B, vitamin C, and vitamin K, and pay attention to preventing, treating and correcting dehydration, electrolyte imbalance and shock. Severely ill patients should undergo hemodialysis as soon as possible, which can effectively remove arsenic from the blood and prevent and treat acute renal failure.

5. Patients poisoned by hydrogen arsenide should receive oxygen inhalation and intravenous drip of 400-600 mg of hydrocortisone or 10-20 mg of methylprednisolone to inhibit hemolytic reaction. If hemoglobin drops to 5g, blood transfusion should be given.

6. Chronic arsenic poisoning can be treated with 10% sodium thiosulfate injected intravenously to assist renal excretion. Skin or mucous membrane lesions can be applied topically with 2.5% dimercaprol ointment or dexamethasone ointment. When multiple peripheral neuropathy occurs, symptomatic treatment is given.