Fungal esophagitis is a special type of esophagitis and an infectious disease. It is not common in daily life, so most people do not know much about the causes of fungal esophagitis. In fact, the occurrence of fungal esophagitis is caused by the following four factors, among which the most common reason is that the patient has used broad-spectrum antibiotics for a long time and in large doses. First, the patient had used broad-spectrum antibiotics for a long time and in large doses. Long-term, high-dose use of broad-spectrum antibiotics can disrupt the body's balance and inhibit sensitive bacteria in the body. If certain Gram-negative bacteria that can produce antifungal substances are inhibited, the fungal reproduction rate will accelerate, thus causing fungal esophagitis. Second, the patient had used large amounts of adrenal cortical hormones for a long time. Long-term use of large amounts of adrenal cortical hormones can promote the lysis of neutrophils and macrophages, reduce antibodies, and increase the toxic effects of molds. Third, the patient had been exposed to large doses of radiation and used immunosuppressants. High-dose radiation exposure and the use of immunosuppressants can cause a decrease in the number of neutrophils and macrophages, and even directly damage normal tissues and cells, creating conditions for fungal infection. Fourthly, malnutrition, aging, wasting diseases, surgery, etc. can lead to low cellular immune function of the body, reduce the phagocytic and bactericidal function of white blood cells, and provide the possibility for the onset of fungal esophagitis. The infection route of fungal esophagitis can be divided into exogenous and endogenous types, and the onset of the disease can be divided into primary and secondary types. Most patients with fungal esophagitis suffer from primary exogenous infection without any predisposing factors, with localized lesions and a good prognosis. In contrast, secondary fungal esophagitis is mostly endogenous infection, often with disseminated lesions, low patient resistance and poor prognosis. The main symptoms of fungal esophagitis are sore throat, dysphagia, odynophagia, sometimes accompanied by pain behind the sternum. |
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