Why do cells gradually become senescent?

Cells are the basic units that make up our body. Cells change as we age and enter the aging period. A question we often ask is, at what stage do cells age? We usually always want to find better answers to these questions. Next, I will explain to you why cells age, so that you can learn more about issues such as the biosphere and not be troubled by it.

Since the 1990s, significant progress has been made in the research on the mechanisms of cellular aging. Scientists have proposed many hypotheses, and the ones that are currently generally accepted are the free radical theory and the telomere theory. Free Radical Theory

We usually call abnormally active charged molecules or genes free radicals. Free radicals contain unpaired electrons and are highly reactive. In life activities,

Cells are constantly undergoing various oxidation reactions, in which free radicals are easily produced. In addition, radiation and invasion of harmful substances can also stimulate cells to produce free radicals. For example, water produces free radicals when exposed to ionizing radiation.

Once generated, free radicals attack and destroy various biological molecules within cells that perform normal functions. What is most serious is that when free radicals attack the phospholipid molecules that are components of biological membranes, the products are also free radicals.

These newly generated free radicals will attack other molecules, thereby triggering an avalanche reaction that causes considerable damage to the biofilm. In addition, free radicals can attack DNA and may cause gene mutations;

Attacks proteins, causing protein activity to decrease and leading to cell aging. Telomere theory: There is a special sequence of DNA at both ends of each chromosome, called telomere.

Telomere DNA sequences shorten after each cell division. As the number of cell divisions increases, the truncated part will gradually extend inward. After the telomere DNA sequence is "truncated", the inner part of the telomere

The DNA sequence of normal genes will be damaged, resulting in the cell function becoming abnormal.

This is the reason for cell aging. Have you understood it through the above content? When we encounter such problems, we should solve the doubts in our minds as soon as possible. Cells can only be observed through a microscope, and they are very small. To put it more directly, cell aging means the end of life, which can be divided into acute and chronic, so this is the cause of cell aging.