Treatment of duodenal ulcer

In life, some patients are troubled by duodenal ulcer. Duodenal ulcer (DU) is one of the common chronic diseases. It is a defect in the duodenal mucosal layer and muscular layer caused by various factors. Next, I will introduce to you the treatment methods of duodenal ulcer.

Diet therapy: 1. It is advisable to eat soft and easily digestible foods, and avoid large, hard, and crude fiber-rich foods to reduce mechanical stimulation to the ulcer surface.

2. Choose fruits and vegetables that are low in fiber, such as tender cucumbers, tender eggplants, tender cabbage leaves, tomatoes (peeled and seeded), winter melons, and carrots.

3. Avoid foods that can strongly stimulate the secretion of gastric juice, such as coffee, strong tea, cocoa, chocolate, thick broth, chicken soup, overly sweet foods, alcohol, sweet potatoes and other foods; various spices and strong condiments, such as MSG, mustard, pepper, chili, fennel, pepper, etc. should also be controlled.

4. Foods high in crude fiber, such as cornmeal, sorghum rice and other whole grains, dried soybeans, wild rice, bamboo shoots, celery, lotus root, leek, soybean sprouts, etc. should be limited. Hard foods, such as bacon, ham, raw onions, raw garlic, raw radishes, onions, garlic sprouts and other gas-producing foods are not good for ulcers.

5. Avoid overly sweet, overly salty, overly hot, and cold foods.

1. Quit smoking. The incidence of ulcers in smokers is twice as high as that in non-smokers. Smoking affects ulcer healing and can promote ulcer recurrence. The possible mechanism is:

(1) Smoking can increase the secretion of gastric acid and pepsinogen.

(2) Smoking may inhibit the pancreas from secreting HCO3- salts, thereby weakening its ability to neutralize the acidic fluid in the bulb.

(3) Smoking can affect the closing function of the pyloric sphincter, leading to bile reflux and damaging the gastric mucosal barrier; smoking can delay gastric emptying and affect the gastroduodenal motility function.

(4) Smoking can affect the synthesis of prostaglandins in the gastric and duodenal mucosa, reduce the amount of mucus and mucosal blood flow, and thus reduce the defensive function of the mucosa.

2. Diet control: drinks such as alcohol, coffee, strong tea, and Coca-Cola can stimulate increased gastric acid secretion and easily induce ulcers. People who eat a refined, low-fiber diet have a higher incidence of ulcers than those who eat a high-fiber diet. Some people believe that foods high in residue may promote the release of epidermal growth factor or prostaglandins.

3. Mental factors: People who suffer from long-term mental stress, anxiety or mood swings are prone to duodenal ulcers. When people are under stress, it may promote the enhancement of gastric secretion and motility, increase gastric acid secretion and accelerate gastric emptying. At the same time, due to the sympathetic nerve excitement, the gastric and duodenal blood vessels contract, the mucosal blood flow decreases, and the mucosal self-defense function is weakened.

4. Medication: About 10% to 25% of patients taking long-term oral non-steroidal anti-inflammatory drugs will develop ulcers, among which gastric ulcers are more common. In addition to the direct stimulatory effect of drugs on the gastroduodenal mucosa, this is mainly because these drugs inhibit the activity of cyclooxygenase in the body, reducing the synthesis of prostaglandins in the mucosa and weakening the protective effect on the mucosa. Aspirin itself is fat-soluble and can penetrate the epithelial cell membrane and destroy the mucosal barrier.

I believe that after reading the above article, everyone must have a certain understanding and knowledge of duodenal ulcer. I hope everyone is in good health.