The appearance of small nodules in the right lower lung always catches patients off guard. If the small nodules in the right lower lung are caused by simple lung inflammation, it is not scary. What is scary is the small nodules in the right lower lung caused by tuberculosis and tumors. The small nodules in the right lower lung caused by these two reasons will directly affect the patient's life and health. Therefore, patients with small nodules in the right lower lung must not be treated carelessly. Sarcoidosis is the result of the conflict between unknown antigens and the body's cellular and humoral immune functions. Due to individual differences (age, gender, race, genetic factors, hormones, HLA) and the regulation of antibody immune response, the development and regression of granulomas are determined by the imbalance between the promoting factors and antagonistic factors produced, showing different pathological states and natural remission trends of sarcoidosis. Sarcoid granulomas may be seen on tissue sections as aggregates of dermoid cells containing multinucleated macrophages surrounded by lymphocytes without caseation. Inclusion bodies, such as oval Schaumann bodies, birefringent crystals and asteroid bodies, can be seen in the vesicles of macrophages. The initial lesions of pulmonary sarcoidosis include extensive alveolitis infiltrated by monocytes, macrophages, and lymphocytes, involving the alveolar walls and interstitium. Both alveolitis and granulomas may resolve on their own. However, in the chronic stage, the fibroblasts surrounding the granulomas become collagenous and hyalinized, becoming nonspecific fibrosis. The histomorphological manifestations of granulomas are not characteristic and can be seen in mycobacterial and fungal infections, or as tissue reactions to foreign bodies or trauma. They can also be seen in beryllium disease, tertiary syphilis, lymphoma, and exogenous allergic alveolitis, and should be differentiated. However, the same tissue lesions are seen in multiple organs, and combined with clinical data, the disease can be diagnosed. Because most patients can recover on their own, patients with stable conditions and no symptoms do not need treatment. Patients with obvious symptoms in stages II and III and extrathoracic sarcoidosis, such as ocular sarcoidosis, sarcoidosis invasion of the nervous system, skin and myocardial involvement, persistent increase in blood calcium and urine calcium, and significantly increased SACE levels can be treated with hormones. The commonly used dose of prednisone is 30 to 60 mg per day, taken orally once (or in divided doses). After 4 weeks, the dose is gradually reduced to 15 to 30 mg per day, and the maintenance dose is 5 to 10 mg per day for one year or longer. Long-term use of glucocorticoids should closely monitor the side effects of the hormones. Secondly, chloroquine, methotrexate, azathioprine, etc. can be used as treatment. 1.2 Any drug that can cause increased blood calcium and urine calcium, such as vitamin D, is contraindicated. Therefore, the question of whether small nodules in the right lower lung are serious depends mainly on the patient's condition. If the patient has chronic small nodules in the right lower lung, it will seriously invade other organs of the body, causing the patient's overall physical condition to be relatively poor. This is a relatively serious condition for the patient. |
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