Experts talk about medication tips for tongue cancer

As a common disease of ENT tumors, the medication and treatment of tongue cancer has always attracted much attention. How to use medication and how to treat it to quickly relieve the pain caused by the disease is a professional issue. As ordinary people who are not in the medical field, we cannot make arbitrary inferences and guesses. Below, we ask experts to talk about the medication techniques for tongue cancer.

The basic treatment for general diseases is through medication, but because tongue cancer belongs to the category of malignant tumors, clinical treatment of tongue cancer is mainly surgical treatment, and the effect of medication is not great. Generally, primary source resection and neck lymph node dissection should be performed, and radiotherapy or chemotherapy and biological immunotherapy should be combined before or after surgery.

Early-stage, well-differentiated tongue cancer can be treated with radiotherapy, simple surgical resection, or cryosurgery. Advanced tongue cancer should be treated with comprehensive treatment, using radiotherapy plus surgery or triple (chemotherapy, surgery, radiotherapy) or quadruple (triple plus traditional Chinese medicine or immunotherapy) therapy according to different conditions.

Biological immunotherapy: During clinical treatment with DC-CIK biological immunotherapy technology, two special functional cells of the human immune system that specifically deal with tumor cells are separated from the human peripheral blood: one is the DC cell, which is like a "radar" that can actively search and identify tumor cells, and transmit information to immune active cells to activate immune responses, enhance the body's immunity, and inhibit tumor generation and spread; the other is the CIK cell, which is like a "missile" that can accurately and targetedly kill tumor cells without damaging any normal tissues. At the same time, it is particularly good at clearing residual and tiny metastatic lesions, effectively preventing the recurrence and metastasis of cancer cells.

Biological cell therapy technology uses DC-CIK cell therapy. DC cells are the initiators of the body's immune response and can induce a long-lasting and powerful specific anti-tumor immune response; CIK cells can eliminate tiny residual lesions in tumor patients through non-specific immune killing. Therefore, the organic combination of DC loaded with tumor antigens and CIK, namely DC-CIK cells, can produce specific and non-specific dual anti-tumor effects. The two have a certain complementary effect, and the combined application can achieve a "1+1>2" therapeutic effect. DC-CIK anti-cancer cell experiments show that the killing activity of DC-CIK cells in killing cancer cells is significantly higher than that of CIK cells, and is equivalent to the cancer cell activity of DC-CIK cells cultured by the PBMC collection method of a blood cell separator.

Radiotherapy: It can be used as an adjuvant treatment before and after surgery for advanced tongue cancer.

Surgical treatment: the main method of treating tongue cancer. For T1 cases, wedge-shaped resection more than 1 cm away from the lesion can be performed and sutured directly; for T2-T4 cases, hemiglossectomy or even total glossectomy should be performed. As an important organ for chewing and speech, reconstruction should be performed when more than 1/2 of the tongue is missing.

For preventive anti-infection in general surgery, sulfonamides or drugs that mainly act on Gram-positive bacteria are used. For surgeries with a large scope and simultaneous bone grafting or complex repairs, combination therapy is generally used. The most commonly used ones are: drugs that act on Gram-positive bacteria + drugs that act on Gram-negative bacteria + drugs that act on anaerobic bacteria. For patients with severe infection before and after surgery, large surgical wounds, and complex repair methods, effective antibiotics can be selected based on clinical practice and drug sensitivity tests.

Chemotherapy: Chemotherapy can be used before or after surgery. Because of its serious side effects, it should be used under the guidance of a physician and with close observation of blood counts. Cryotherapy can be considered for T1 and T2 tongue cancer.

Traditional Chinese medicine treatment: Traditional Chinese medicine can make up for the deficiencies of surgical treatment, radiotherapy, and chemotherapy. It can not only consolidate the effects of radiotherapy and chemotherapy, but also eliminate the toxic side effects of radiotherapy and chemotherapy.