Will my father's stomach cancer be inherited?

Is gastric cancer hereditary? Medical research has found that most gastric cancer patients are middle-aged and elderly people. However, surveys in recent years have shown that the incidence of gastric cancer among young people is on the rise. Because the clinical symptoms of gastric cancer in young people are not typical, especially because young people do not know enough about gastric cancer, the rate of early diagnosis is not high, resulting in more misdiagnosis and missed diagnosis.

The occurrence of gastric cancer in young people in my country is not only related to bad eating habits, environmental factors and other factors, but also has a certain correlation with genetics.

Is stomach cancer hereditary?

In order to analyze and grasp the incidence of gastric cancer in young people, Ren Jun et al. retrieved and analyzed the medical records of 1,839 inpatients diagnosed with gastric cancer in the hospital from 1983 to 2003, and conducted follow-up surveys on the patients. The results showed that among these patients, 247 were under 45 years old (1,745 years old), accounting for 13.43% of the total number of patients. Among them, there were 132 males and 115 females, with an average age of 41.5 years old. Ren Jun et al. conducted further research on these 247 patients according to the genetic standards established by the 1998 Seoul International Genetics Conference. The standards include: at least 3 people in the family suffer from the same disease, one of whom is a direct relative of the other two; at least two consecutive generations have the disease; at least one patient in the family was diagnosed before the age of 45; at least two of the above standards are met. Ren Jun et al. screened 189 patients with complete genetic data from the above patients, including 39 patients with a family genetic disease background and 16 patients who met the hereditary gastric cancer criteria. The two items add up to 55 cases, accounting for 29.1% of the total number of people with complete genetic data.

To study the differences in the occurrence of gastric cancer in young people and genetic diseases in other age groups, Ren Jun et al. compared the young people's gastric cancer group with the middle-aged and elderly people's gastric cancer group. The results showed that among the 1454 patients with complete genetic data in the middle-aged and elderly people's gastric cancer group, 90 cases met the genetic background or hereditary gastric cancer, accounting for 0.6% of the total number of the group. There was a significant difference between the two groups (p<0.001), indicating that the incidence of gastric cancer in young people is not only closely related to the family genetic background, but also that their genetic incidence of gastric cancer is higher than that of middle-aged and elderly people.

Is gastric cancer hereditary? Through the above introduction, I hope everyone can understand the hereditary nature of gastric cancer. At the same time, I hope gastric cancer patients can learn more about the common knowledge about gastric cancer, which will also be beneficial for the treatment of gastric cancer patients.