Briefly outline the causes of rectal cancer

Rectal cancer does not occur suddenly, but is the result of the combined effects of many factors. The causes of rectal cancer may include some congenital genetic factors and acquired bad living habits, which require comprehensive knowledge and understanding. What are the common causes of rectal cancer ? Let's talk about the common causes of rectal cancer.

In general, the common causes of rectal cancer are:

1. Genetic factors: In addition to patients with rectal cancer caused by familial polyposis or malignant transformation of ulcerative colitis, about 5-10% of other rectal cancer patients have a clear family history of tumors, collectively known as hereditary non-polyposis colorectal cancer (HNPCC), also known as Lynch syndrome. The specific manifestations are: (1) three or more family members have rectal cancer, and more than two of them are from the same generation; (2) at least two generations have the disease; (3) at least one of them was diagnosed with rectal cancer before the age of 50. This is a common cause of rectal cancer.

2. Chronic rectal inflammation: Chronic ulcerative colitis and granulomas caused by chronic schistosomiasis are directly related to the cause of rectal cancer. The longer the course of the disease, the higher the possibility of rectal cancer. The incidence of rectal cancer in patients with ulcerative colitis for more than 20 years is about 20-40%.

3. Diet and carcinogens: Epidemiological studies have shown that the cause of colorectal cancer is significantly related to economic conditions and dietary structure. The incidence rate is significantly higher in economically developed areas, areas and groups where the diet has a high proportion of animal fat and protein and a low fiber content. The exact mechanism of the relationship between dietary structure and the cause of colorectal cancer is not yet fully understood. It is generally believed that it may be related to factors such as the metabolites of animal fat, bacterial decomposition products, and the slowing of intestinal peristalsis and increased intestinal toxin absorption due to a low-fiber diet.

The above is a brief introduction to the common causes of rectal cancer. I believe everyone should have a preliminary understanding of this. If you still have questions about the causes of rectal cancer, you can consult our online experts, who will give you detailed answers.