Worsening of gastritis can easily lead to malignant lymphoma

Lymphoma is a malignant tumor that originates in lymph nodes or other lymphatic tissues. If not diagnosed and treated in time, it can be very harmful to the patient's life. Recently, clinical research by medical scientists has found that various chronic inflammations, including gastritis, are hidden causes of malignant lymphoma .

Malignant lymphoma is caused by the cancerous transformation of lymphocytes, which are responsible for immune functions. Researchers at the University of Tokyo have developed a technology that can efficiently detect individual differences in base sequences and used this technology to analyze approximately 300 patients with malignant lymphoma.

The results showed that among patients with malignant lymphomas such as "mucosa-associated lymphoid tissue lymphoma" which mainly occurs in the digestive tract, about 20% of people have mutations in the base sequence of the A20 gene, which causes the A20 gene to not work properly.

The A20 gene acts as a "brake" when inflammation occurs in the human body, preventing lymphocytes from proliferating indefinitely. Researchers transplanted lymphoma cells with inoperative A20 genes into experimental mice. As a result, once the experimental mice developed inflammation, the substances produced by the inflammation stimulated the lymphoma cells, causing them to proliferate abnormally and eventually generate malignant lymphomas. If the experimental mice were implanted with lymphoma cells with inoperative A20 genes but there was no inflammation in their bodies, the lymphoma cells would not proliferate. Therefore, Japanese researchers believe that inflammation is the fuse that triggers certain malignant lymphomas.

Through the analysis of the results of medical research, we can know that there is a certain relationship between the onset of malignant lymphoma and the worsening of chronic inflammatory diseases such as gastritis. I hope that all friends can actively prevent diseases in daily life and avoid the vicious cycle caused by the mutual influence of various diseases.

For more information, please visit the lymphoma disease special topic at http://www..com.cn/zhongliu/lb/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.