Can urine protein 20 be cured?

In life, we often hear many people say that they have been diagnosed with urine protein. Urine protein is very bad because it will cause a large amount of protein in the body to be lost with urine. Most of it comes from functional problems of the kidneys. Excessive urine protein is also harmful. As long as the patient can go to the hospital for examination and treatment in time, recovery will be quick.

Advantages of 24-hour urine protein quantification

24-hour urine protein quantification is very useful for evaluating therapeutic efficacy. In a routine urine test, negative urine protein corresponds to a urine protein quantification of less than 0.5g. A value above one + cannot fully estimate the amount of urine protein. For example, after one month of treatment, the patient's urine protein is still ++++++, but if the urine protein quantification drops from more than 10g to 4-5g, this indicates that the treatment is still effective. Sometimes the urine protein drops from ++++++ to ++++, but this does not necessarily mean that it is effective. Especially after the urine protein (routine test) turns negative, a routine urine test can no longer explain the problem. Only by using urine protein quantification can it be determined whether the urine protein has truly turned negative. Treatment takes time, etc.

1. Due to glomerular diseases, the glomerular filtration membrane or charge barrier is damaged, and a large amount of plasma protein will be filtered into the urine, resulting in proteinuria, which is called pathological glomerular proteinuria. It is more common in acute and chronic glomerulonephritis, glomerular nephropathy, and secondary glomerular diseases such as diabetic nephropathy, lupus nephritis, and renal amyloid degeneration.

2. In addition to glomerular proteinuria, pathological urine protein also includes tubular proteinuria, overflow proteinuria, and renal tissue proteinuria. Tubular proteinuria is caused by dysfunction of tubular protein reabsorption under pathological conditions and is more common in diseases of the renal tubules and interstitium. Overflow proteinuria is caused by a pathological condition in which certain small molecular proteins in the plasma increase significantly and exceed the reabsorption capacity of the renal tubules and enter the urine, forming proteinuria. It is common in diseases such as multiple myeloma and severe crush injuries. Renal tissue proteinuria refers to the entry of renal tissue protein into the urine or the secretion of protein into the urine by the renal tissue under pathological conditions.

1. Diagnosis:

1. In glomerular proteinuria, the amount of urine protein is generally higher, mainly albumin; in tubular proteinuria, the amount of urine protein is lower, mainly lysozyme, β2-microglobulin, etc.; renal tissue proteinuria often does not exist alone, but often exists simultaneously with glomerular or tubular proteinuria; overflow proteinuria is caused by primary disease and is a special protein.

2. Urine protein is the protein detected when urine becomes turbid after being acidified and heated. The normal 24-hour urine protein range is ≤0.15g, and routine urine protein tests are negative. If the urine protein test is > 150 mg/day, that is, the urine protein is positive, it means that the amount of urine protein excreted by the human body has increased significantly, which is abnormal urine protein. Persistent positive urine protein often indicates kidney disease. Therefore, clinically, the degree of kidney damage and the effectiveness of kidney disease treatment can be determined based on the amount of positive urine protein.

2. Prevention:

1. Prevention of acute nephritis: mainly prevent and treat other related diseases that can cause nephritis (also known as precursor diseases of nephritis), especially some diseases caused by hemolytic streptococcal infection, such as upper respiratory tract infection, acute tonsillitis, pharyngitis, scarlet fever, erysipelas abscess, etc. If it is confirmed that acute nephritis is caused by tonsillitis, tonsillectomy when appropriate will help cure and prevent recurrence. Other bacteria, viruses, protozoa, etc. can also cause nephritis. Therefore, active and timely prevention and treatment of precursor diseases that cause nephritis are important for preventing the occurrence of acute nephritis and preventing acute nephritis from turning into chronic nephritis.

2. The most fundamental way to prevent chronic nephritis is to improve the body's ability to resist disease and reduce the chance of infection by preventing the cause: