What does lymphoproliferative lesion mean

Lymph is a word that everyone is very familiar with. When we have a cold, fever or getting angry, there will be some symptoms of lymphadenitis, so people are not afraid of it. However, many people are not familiar with what lymphoproliferative disease is. When they mention the disease, they are afraid that it is cancer. This disease still needs to be judged based on the severity. This article introduces the relevant knowledge about lymphoproliferation. If you don’t understand, take a look.

fever

Except for extremely mild cases, all patients have fever, with body temperature ranging from 38.5~40℃, which may be remittent, irregular or persistent, and the fever course may range from several days to several weeks. There may be a relatively slow pulse in the early stage of the disease.

Swollen lymph nodes

60% of patients have superficial lymphadenopathy. Lymph nodes throughout the body can be affected, with cervical lymph nodes being the most common, followed by axillary and groin lymph nodes, and thoracic, mediastinal, and mesenteric lymph nodes occasionally being involved. The diameter is 1~4cm, of medium hardness, scattered without adhesion, without obvious tenderness, without suppuration, and asymmetrical on both sides. The swollen lymph nodes will gradually subside, usually within 3 weeks, but occasionally it may last longer.

Pharyngitis

About half of the patients have congestion, edema or swelling of the pharynx, uvula, tonsils, etc., and a few have ulcers or pseudomembrane formation. Whenever the patient has sore throat, small bleeding spots may be seen on the palate, and the gums may also be swollen and ulcerated. Laryngeal and tracheal obstruction is rare.

Hepatosplenomegaly

About 10% of cases have hepatomegaly, 2/3 of cases have abnormal liver function, and about 5% to 15% have jaundice. Almost all cases have splenomegaly, which is usually only 2 to 3 cm below the costal margin, and spleen rupture may occasionally occur.

Understanding the nature of lymphadenopathy is also important for the diagnosis of the disease. If it is an acute or chronic inflammation, the lymph nodes are soft and movable, have no adhesion to the surrounding tissues and skin, and have a sense of freedom. In the acute phase, there are typical symptoms of redness, swelling, heat and pain. In the early stages of lymph node tuberculosis, there is no adhesion to the skin and surrounding tissues, but the disease may continue to swell as it worsens. But it does not exceed the size of a walnut. Later, it may adhere and fuse into pieces, change, rupture, and discharge yellow-brown pus or tofu-like substances. Lymph node swelling caused by cancer is mostly hard like stone, with uneven appearance, and may adhere to the skin, without pain or tenderness. In lymphocytic leukemia, the swollen lymph nodes are movable, non-sticky, smooth, not hard, not painful, and do not fester or ulcerate.