Many people may not have used isotretinoin, and of course they don't know what it is for treatment. It should be noted that no matter which drug is used, it is necessary to first look at the drug's intended use and precautions to avoid side effects caused by the drug. Drugs such as isotretinoin have great therapeutic value for acne removal because they can effectively inhibit the secretion of sebum. Isotretinoin gel is mainly used for the treatment of local acne vulgaris and acne. Generally, apply a small amount to the affected area 1-2 times a day. A course of treatment is 5-8 weeks. The effect of treating acne is quite good after using it according to the course of treatment. The main active ingredient of isotretinoin gel is isotretinoin. When used to treat acne, isotretinoin can shrink sebaceous gland tissue, inhibit sebaceous gland activity, reduce sebum secretion, reduce epithelial cell keratinization and keratin plugging at the opening of the sebaceous glands of hair follicles, and inhibit the growth and reproduction of Propionibacterium acnes. Recent studies have also shown that this drug can regulate inflammatory immune mediators related to the pathogenesis of acne and selectively bind to retinoic acid nuclear receptors to exert a therapeutic effect. When used topically, the mode of action of isotretinoin may be similar to that of its stereoisomer tretinoin. Retinoic acid can induce epidermal cell proliferation; promote the differentiation of epidermal granular layer cells into the stratum corneum; and remove keratin plugs by regulating the abnormal keratinization process of the sebaceous gland epithelium of the hair follicles, thereby preventing, treating and eliminating acne lesions. When you first start using isotretinoin gel, you may experience a burning sensation or mild to moderate irritation, redness, or peeling. These reactions may disappear after you stop taking the drug. If irritation persists and is severe, stop taking the medication and consult a doctor. Do not use on broken, eczematous or sun-burned skin. It is forbidden to use for pregnant and lactating women. From the above information, it can be concluded that the acne removal effect of isotretinoin gel is quite significant. It is recommended that patients clean the affected skin before using isotretinoin gel. Do not use cosmetics during medication and avoid using fluorescent lamps. Eating more foods rich in vitamin B can promote skin repair. |
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