What should I do if I drink alcohol while receiving cephalosporin infusion? How should I treat drinking alcohol while receiving cephalosporin infusion? How should I treat it?

There are more and more antibiotics in society now, most of which are cephalosporin antibiotics. Antibiotics should not be used indiscriminately. Once used indiscriminately, shock is likely to occur, and in severe cases, life safety may be endangered. If you use cephalexin during intravenous infusion, you need to abstain from alcohol because there are many adverse reactions between cephalexin and alcohol. What if you drink alcohol?

1. Do not drink alcohol after infusion of cephalosporins, because cephalosporins and alcohol can produce a disulfiram reaction, which can cause death in severe cases.

2. Don't drink alcohol one week after the infusion, so there is basically no possibility of a disulfiram reaction.

3. Alcohol can enhance the liver's detoxification function and reduce the efficacy of the drug, so drinking is prohibited during medication.

4. Drinking something containing alcohol after taking medicine can lead to accumulation of acetaldehyde in the body and cause poisoning. After alcohol enters the body, it is first oxidized into acetaldehyde by the action of "alcohol dehydrogenase" in the liver cells. Acetaldehyde is oxidized into acetic acid and acetaldehydease A by the action of acetaldehyde dehydrogenase in the mitochondria of the liver cells. Acetic acid is further metabolized into carbon dioxide and water and excreted from the body. After acetaldehyde is produced, it cannot be further oxidized and metabolized, which leads to the accumulation of acetaldehyde in the body and the occurrence of a disulfiram-like reaction. Symptoms include facial flushing, conjunctival congestion, blurred vision, violent pulsation of blood vessels in the head and neck, fluctuating headaches, dizziness, nausea, vomiting, sweating, dry mouth, chest pain, myocardial infarction, acute heart failure, difficulty breathing, acute liver damage, convulsions and even death.

Disulfiram-like reaction, also known as disulfiram-like reaction, is a poisoning reaction caused by "acetaldehyde accumulation" in the body after taking drugs (cephalosporins) and drinking beverages containing alcohol (or coming into contact with alcohol). After alcohol enters the body, it is first oxidized into "acetaldehyde" by the action of "alcohol dehydrogenase" in the liver cells. Acetaldehyde is oxidized into "acetaldehyde and acetaldehydease A" by the action of "acetaldehyde dehydrogenase" in the mitochondria of the liver cells. Acetic acid is further metabolized into carbon dioxide and water and excreted from the body. Because some chemical structures contain "methylthiotetrazolyl side chain", the activity of acetaldehyde dehydrogenase in the mitochondria of liver cells is inhibited, so that acetaldehyde cannot be further oxidized and metabolized after it is produced, thereby leading to the accumulation of acetaldehyde in the body and the occurrence of a disulfiram-like reaction. When disulfiram is absorbed in trace amounts by the human body, it can cause symptoms such as facial flushing, headache, abdominal pain, sweating, palpitations, and difficulty breathing, especially after drinking alcohol, the symptoms will be more obvious. People call the symptoms that occur after drinking alcohol after exposure to disulfiram a disulfiram-like reaction. Don't worry as long as you don't have any discomfort. Just drink more water and promote metabolism.