Gout is caused by these reasons

Most people know that gout is the culprit of joint pain, but they don’t know what the culprit is. The first is high uric acid. Once a person’s body has high uric acid, the condition of gout patients will worsen. This has a lot to do with the body’s blood flow and the composition of the blood. Long-term ventilation can cause tumors, erythema, and frequent attacks of gout, leading to joint movement injuries. Early diagnosis and treatment are needed promptly.

Do you know what is the culprit of gout?

The answer is uric acid, that is, the onset of gout is mainly related to high blood uric acid.

The vast majority of gout patients will exhibit hyperuricemia for at least some period of time. Generally speaking, the higher the blood uric acid concentration and the longer it lasts, the more likely you are to develop gout and the more severe the gout symptoms will be. For example, some statistics have found that if the blood uric acid concentration is continuously higher than 540 micromol/L, about 70% to 90% of people will experience gout attacks. Therefore, hyperuricemia is an important biochemical characteristic of gout, and increased blood uric acid is the most important basis for diagnosing gout.

On the other hand, although the blood uric acid levels of most patients with gout attacks are significantly higher than normal (420 μmol/L), not all patients with hyperuricemia will experience gout symptoms. 90% of patients with hyperuricemia do not have symptoms of gout attacks, which is called asymptomatic hyperuricemia; while some patients have blood uric acid levels within the normal range during acute gout attacks. There are even reports that gout patients with low blood uric acid levels account for more than half of all gout patients.

Therefore, we cannot exclude the diagnosis of gouty arthritis just because the blood uric acid level is normal, nor can we diagnose all patients with elevated blood uric acid as having gout; a correct judgment should be made based on the patient's medical history, symptoms, signs and other examination results.

It is particularly noteworthy that there are many people with hyperuricemia. Some people may have joint swelling and pain due to other reasons, but they also have hyperuricemia at other times. At this time, we cannot hastily assume that the joint pain is a gout attack. We should combine other manifestations to rule out diseases such as tumors and systemic lupus erythematosus.

Early diagnosis of gout

1. Clinical diagnosis criteria for acute gout: Recurrent acute arthritis accompanied by increased blood uric acid, which is effectively treated with colchicine and Tongfengqing, that is, within a few hours of an acute attack of arthritis, take 0.5-1 mg of colchicine every 1-2 hours. If it is acute gout, generally after taking the medicine 2-3 times, the joint pain will immediately stop, and the patient will be able to walk from being unable to walk.

2. Standards proposed by the American College of Rheumatology: The presence of specific urate crystals or tophi in the joint fluid, confirmed by chemical methods or polarized light microscopy. The diagnosis can be confirmed if one of the above three items is met. Patients with 6 of the following 12 clinical, laboratory and X-ray signs can be diagnosed with gout:

⑴ More than one acute arthritis attack. ⑵Inflammatory symptoms reach a peak within 1 day. ⑶Attack of monoarthritis. ⑷ Redness of the joints was observed. ⑸Pain or swelling in the first metatarsophalangeal joint. ⑹Unilateral attack involves the first metatarsophalangeal joint. (7) Unilateral onset involving the tarsal joint. ⑻ Suspected tophi. ⑼Hyperuricemia. ⑽X-ray examination of asymmetric swelling within the joint. ⑾Subcortical cysts are not accompanied by bone erosion. ⑿ During joint attacks, the microbial culture of the joint fluid is negative. ⒀Typical gouty foot, i.e. arthritis of the first metatarsophalangeal joint, accompanied by swelling of the soft tissue around the joint.