Does hepatitis B virus DNA positive need to be treated

Does hepatitis B virus DNA positive need to be treated

There are many types of DNA viruses, and hepatitis B virus is one of the manifestations of DNA viruses. When the hepatitis B virus DNA is positive, the patient can be confirmed to be infected with the hepatitis B virus. At this time, his blood and body fluids are easily transmitted to other people. In this case, the patient must receive good treatment to avoid greater harm to his health.

1. The significance of hepatitis B virus DNA test

Hepatitis B virus DNA is the deoxyribonucleic acid of hepatitis B virus (i.e. hepatitis B virus gene). Hepatitis B virus DNA is the most direct, specific and sensitive indicator of HBV infection. HBV DNA determination is the best indicator that directly reflects the replication status and infectiousness of HBV, and plays a major role in the treatment of hepatitis B. The HBV DNA content can directly reflect the amount of virus present in the body, whether it is contagious, and how infectious it is. Hepatitis B virus DNA is positive, indicating HBV replication and infectiousness. A high level of hepatitis B virus DNA means the virus replicates more vigorously and is more contagious.

2. Hepatitis B virus DNA positivity cannot reflect the degree of liver damage

It can only reflect the degree of HBV replication and the strength of its infectiousness, but cannot reflect the degree of liver damage. It is not possible to judge how to treat HBV DNA positivity based solely on whether the HBV DNA is positive or not. To understand how to treat hepatitis B virus DNA positivity, a comprehensive analysis of the results of liver function, B-ultrasound, liver puncture and other tests is needed.

For patients with normal liver function but positive hepatitis B virus DNA, if the B-ultrasound is normal and liver puncture shows no liver inflammation, some immune-enhancing and liver-protecting treatments can be sufficient. You must pay attention to regular checks of liver function, B-ultrasound, alpha-fetoprotein, etc., pay close attention to changes in the disease, and promptly carry out hepatitis B antiviral treatment if liver lesions are found.

3. If there is obvious inflammatory activity in the liver, antiviral treatment is required

If the B-ultrasound of a patient with positive hepatitis B virus DNA indicates cirrhosis, or the results of a liver puncture examination show inflammation of the liver, antiviral treatment is required even if the liver function is normal. Long-term liver inflammation can lead to liver fibrosis. When liver fibrosis accumulates to a certain extent, it can cause cirrhosis and even liver cancer. Therefore, it is very necessary for patients with positive hepatitis B virus DNA but normal liver function to undergo liver puncture examination to determine whether there is inflammation in the liver.

4. People with abnormal liver function also need treatment

In addition, if the hepatitis B virus DNA is positive and the liver function is abnormal, the liver of the hepatitis B patient is severely damaged and the virus replication in the body is active, antiviral treatment is necessary. For the antiviral treatment of hepatitis B, Klebsiella pneumoniae's highly effective negative conversion therapy uses the latest gene segmentation-guided technology, which can isolate viral genes in the shortest time. At the same time, the use of gene bombs to actively and targetedly eliminate hepatitis B virus is rapid and effective. Therefore, compared with traditional therapies, the therapeutic effect of Klebsiella pneumoniae's highly effective negative conversion therapy is more than 6 times better.

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