What medicine can I take to relieve vomiting after chemotherapy

Chemotherapy can play a very good therapeutic role in cancer because it mainly uses chemical drugs to kill human cancer cells. Therefore, in the early stages of cancer, doctors generally recommend chemotherapy to patients. Chemotherapy has many side effects, of which vomiting is the most common side effect of chemotherapy. This kind of vomiting will make the patient very uncomfortable, so what medicine should be taken to relieve the vomiting caused by chemotherapy?

If cancer patients experience nausea and vomiting during chemotherapy, they should not eat for at least a few hours before chemotherapy. If vomiting occurs while lying in bed, they should lie on their side to prevent vomitus from being accidentally inhaled into the trachea. After vomiting, the patient should be assisted in rinsing his mouth, and the amount and nature of the vomitus should be recorded. If necessary, a small amount of vomitus should be kept for laboratory testing.

1. Highly emetic drugs: DDP, DTIC, HN2, CTX

2. Moderately emetic drugs: CBP, IFO, ADM, DRN, TAX, HMM, PCB, CCNU

3. Low-grade emetics: VP-16, MTX, 5-FU, MMC, CLB, BLM, MA, VLB, VCR

Commonly used single drugs for nausea and vomiting include:

1. Metoclopramide: the most commonly used antiemetic; it works by blocking central dopamine receptors. Recommended: 10 mg, once, 3 times/day. Main disadvantage: Extrapyramidal symptoms occur.

2. Metoclopramide: 5-HT3 receptor antagonist, which can act on both central and peripheral 5-HT3 receptors. Its antiemetic effect is often better than that of metoclopramide, and it is effective in controlling acute vomiting. Its effect on delayed vomiting remains to be confirmed. Recommended use: mostly used with other antiemetics. Main disadvantages: constipation and headache.

3. Dexamethasone: a glucocorticoid with an unknown mechanism of action. The antiemetic effect is definite. Recommended usage: 4-20 mg once, orally or intravenously.

4. Diazepam: It is used for its sedative and anti-anxiety effects, especially for early vomiting. Take 2.5-5 mg each time, 1-3 times a day, orally, or 5-10 mg each time, intramuscularly or intravenously, once a day.

5. Diphenhydramine: blocks the H1 receptor of the vomiting center and has a synergistic effect on dopamine receptor antagonists. Recommended use: 25-50 mg each time, 2-3 times a day, orally or intramuscularly. Administer 25-50 mg intramuscularly every 3-4 hours until vomiting stops. Main disadvantages: postural hypotension, not suitable for use with metoclopramide.

6. Medroxyprogesterone acetate: The mechanism is unclear. It has a definite therapeutic effect when used in combination with antiemetics and can improve the patient's appetite. Recommended use: 250 mg, once, twice a day, orally, starting 1 day before chemotherapy and stopping 2 days after the end of chemotherapy.

At the same time, it is best not to eat (or smell less) greasy food on the day of intravenous chemotherapy. You can eat more sour and salty side dishes to stimulate the stomach and increase appetite.