Vulvar atrophy has a great impact on women, causing pain during sexual intercourse, especially in middle-aged and elderly women who are experiencing menopause, which can easily cause vulvar atrophy. Endocrine disorders, vulvar infections, and inflammatory stimulation can also lead to vulvar atrophy. 1. Endocrine disorders: When pathological abnormalities occur in the endocrine glands or tissues themselves or problems occur in the immune function, it is easy to cause endocrine disorders, which in turn lead to endocrine diseases. There is a tissue-specific protein hormone called "inhibitin" in the dermis that can inhibit the division and growth of epidermal cells and only acts locally on the epidermis. Endocrine disorders cause an imbalance between local connective tissue hyperplasia and the stimulation of epidermal metabolism in that area, leading to vulvar leukoplakia. 2. Vulvar infection and inflammation: There are many factors that cause vulvar infection and inflammation, such as poor hygiene habits, unclean sexual life, wearing chemical fiber underwear, unclean sanitary products, bathing in a bathhouse, swimming in a bathhouse, etc., which lead to vaginal inflammation. If not treated in time, the inflammatory secretions will infiltrate into the perineum. Long-term infection and stimulation will damage the skin and mucous membranes, causing redness, swelling, ulcers and lesions, and forming vulvar leukoplakia. 3. Family inheritance: About 10% to 30% of patients suffer from vulvar leukoplakia due to inheritance or intergenerational inheritance, and the hereditary-induced vulvar leukoplakia is mainly atrophic vulvar leukoplakia, and patients are more common in young girls. Therefore, in clinical practice, for patients with vulvar leukoplakia under the age of 15, doctors should first consider family genetic factors, inquire whether there are patients with vulvar leukoplakia in the patient's parents' family, and then carry out specific treatment after confirming the cause. 4. Inflammatory stimulation: Inflammation can cause local nerve and blood vessel damage in the pudendum. A small number of parturients may suffer from trichomoniasis, candidal vaginitis, cervical erosion and other inflammations, which can cause increased vaginal secretions and abnormal leucorrhea. Long-term irritation to the vulva can cause vulvar leukoplakia. 5. Perineal trauma: The female perineum may be traumatized due to certain factors. For example, vaginal delivery during pregnancy may cause perineal tearing, which may damage the local nerves and blood vessels of the perineum, and may lead to vulvar leukoplakia. However, this phenomenon is relatively rare in clinical practice, so female friends can rest assured. |
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