Diagnostic criteria and methods for liver failure

Of course, for liver failure, we must pay attention to correct diagnosis and treatment. Common liver failure can manifest as acute liver failure, subacute liver failure, chronic liver failure and other different types, so we must pay attention to treatment according to symptoms.

(1) Acute liver failure

Acute onset, hepatic encephalopathy of grade II or above (classified according to grade IV classification) within 2 weeks and the following manifestations:

① Extreme fatigue, with obvious anorexia, abdominal distension, nausea, vomiting and other severe gastrointestinal symptoms.

② Jaundice progressively worsens in a short period of time.

③ Obvious bleeding tendency, PTA ≤ 40%, and other causes are excluded.

④The liver progressively shrinks.

(2) Subacute liver failure

The onset is more acute, with the following symptoms appearing within 15 days to 26 weeks:

① Extreme fatigue with obvious gastrointestinal symptoms.

② Jaundice rapidly worsens, with serum total bilirubin exceeding 10 times the upper limit of normal or rising by ≥17.1 μmol/L per day.

③ The prothrombin time is significantly prolonged, PTA ≤ 40%, and other causes are excluded.

What are the obvious symptoms of liver failure?

(3) Acute-on-chronic (subacute) liver failure

The main clinical manifestation of acute liver decompensation occurring in a short period of time on the basis of chronic liver disease.

(4) Chronic liver failure

On the basis of cirrhosis, liver function progressively declines and decompensates. The key points of diagnosis are:

① There is ascites or other manifestations of portal hypertension.

② May have hepatic encephalopathy.

③ Serum total bilirubin increased and albumin decreased significantly.

④There is coagulation dysfunction, PTA ≤ 40%.