In recent years, the number of patients suffering from pityriasis capitis has increased. In fact, we can treat this disease with antifungal drugs. You can also use some keratin exfoliants or dandruff cell growth inhibitors to relieve the condition. 1. Antifungal drugs Currently, the antifungal drugs used clinically to treat dandruff include ketoconazole, climbazole, selenium disulfide, etc. Among them, ketoconazole is the most effective in treating dandruff. At low concentrations, ketoconazole can inhibit the synthesis of fungal ergosterol, thereby inhibiting the reproduction of Malassezia; at high concentrations, it can directly destroy the fungal cell membrane and exhibit a strong bactericidal effect. Ketoconazole has a high affinity for scalp proteins and can quickly form a protective film on the surface of the scalp, thereby exerting its effect continuously. In addition, ketoconazole does not undergo transdermal absorption and is highly safe. 2. Cuticle peeling agent Keratolytics can effectively remove a certain proportion of stratum corneum cells and relieve clinical symptoms to a certain extent. Such products include coal tar, sulfur and salicylic acid. Long-term use of such products will damage the epidermal structure, disrupt the epidermis' own balance, and affect hair quality. 3. Dandruff cell growth inhibitor Cytostatics mainly reduce the rate of stratum corneum cell replacement. As the length of the stratum corneum cycle is restored, the process of keratinization and desquamation is improved. However, many clinical experiments have shown that this type of drug cannot effectively control the clinical symptoms of dandruff. Moreover, its main ingredients are highly irritating, and the hair feels rough after use. It may also cause some cosmetic problems, especially for some sensitive skins, and there is an odor. |
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