Can Omeprazole Enteric-coated Capsules be taken before meals?

Omeprazole enteric-coated capsules, what are omeprazole enteric-coated capsules? What are the functions of Omeprazole Enteric-coated Capsules? I believe that everyone does not understand this capsule very well before using it. After all, it is a professional term in medicine. We still need to know something about the efficacy and function of this drug. Let’s take a look at the instructions for Omeprazole Enteric-coated Capsules.

【Drug name】Generic name: Omeprazole enteric-coated capsules

[Pharmacological action] This product is a H+, K+-ATPase proton pump inhibitor. After being absorbed by the small intestine, it circulates through the blood and concentrates in the stomach wall, thereby inhibiting gastric acid.

[Pharmacokinetics] After oral administration, this product is absorbed through the small intestine and takes effect within 1 hour. The blood concentration reaches the peak value in 0.5 to 3.5 hours. The effect lasts for more than 24 hours. It can be distributed to tissues such as the liver, kidney, stomach, duodenum, and thyroid gland, and can easily pass through the placenta.

The bioavailability of a single dose is usually about 35%, and that of multiple doses increases to about 60%. The plasma protein binding rate is 95% to 96%, and the plasma half-life is 0.5 to 1 hour, and 3 hours in patients with chronic liver disease. This product is metabolized in the body by the liver microsomal cytochrome P450 oxidase system, with about 80% of the metabolites excreted via urine and the rest secreted via bile and then excreted in the feces.

[Indications] Used for short-term relief of heartburn and acid reflux symptoms caused by excessive gastric acid.

【Usage and Dosage】Oral. Adults: 1 tablet at a time, once a day (every 24 hours), and 1 more tablet may be taken if necessary, with warm water. This product must be swallowed whole and should not be chewed or crushed. It should not be crushed and taken with food.

[Adverse Reactions] Common adverse reactions of this product are: headache, diarrhea, nausea, vomiting, constipation, abdominal pain and bloating. Occasionally, dizziness, drowsiness, fatigue, sleep disorders, paresthesia, rash, itching, urticaria, abnormal liver function tests, etc. may occur.

Rare: Hyperhidrosis, peripheral angioedema, hyponatremia; angioedema, fever and anaphylactic shock; leukopenia, thrombocytopenia, agranulocytosis, pancytopenia; reversible confusion, irritability, depression, aggression and hallucinations; gynecomastia in men; dry mouth, dysgeusia, stomatitis, candidiasis.

Hair loss, photosensitivity, erythema multiforme; hepatic encephalopathy (previous severe liver disease), icteric or non-icteric hepatitis, liver failure; bronchospasm; arthralgia, myalgia, muscle fatigue; interstitial nephritis; blurred vision.

[Contraindications] This product is contraindicated for patients who are allergic to it, those with severe renal insufficiency and infants.

[Precautions] 1. Do not use for more than 7 days. If symptoms do not improve or disappear, please consult a doctor or pharmacist.

2. Do not take it again within two months. If symptoms recur, seek medical attention immediately.

3. Do not use this product in the following cases: difficulty or pain in swallowing; vomiting blood; bloody or black stools. These may be signs of a serious condition, consult your doctor.

4. Patients with impaired liver function or abnormal blood count should use this product under the guidance of a physician.

5. If heartburn persists or worsens, please stop using this product and go to the hospital for treatment.

6. Children should use this product under the guidance of a physician.

7. Use with caution during pregnancy or lactation.

8. In case of overdose or serious adverse reactions, please seek medical attention immediately.

9. People who are allergic to this product are forbidden to use it, and those with allergic constitution should use it with caution.

10. It is forbidden to use this product when its properties change.

11. Please keep this product out of reach of children.

12. Children must use this product under adult supervision.

13. If you are using other medicines, please consult your physician or pharmacist before using this product.

[Interactions] 1. Avoid simultaneous use with oral imidazole antifungal drugs such as ketoconazole, itraconazole, miconazole and fluconazole.

2. The combined use of omeprazole and clarithromycin can increase the incidence of adverse reactions of the central nervous system (mainly headache) and gastrointestinal tract.

3. Avoid using it simultaneously with diazepam (Valium), phenytoin, warfarin, nifedipine, digoxin, cisapride, quinidine, cyclosporine, caffeine and theophylline.

4. If used with other drugs, drug interactions may occur. Please consult your physician or pharmacist for details.

[Use during pregnancy and lactation] Although animal experiments have shown that this product has no fetal toxicity or teratogenicity, it is generally not used for pregnant women and should be used with caution for lactating women.

[Use in Children] There is no experience in using this medicine in children and it is prohibited for use in infants and young children.

Finally, the editor would like to explain to everyone that this medicine is usually taken before meals. It is recommended to go to the gastroenterology department of the hospital for a check-up to determine whether you need to take this medicine, and follow the doctor's instructions to make reasonable arrangements for taking it. You must know that all medicines are toxic to some extent, so you should not blindly increase or decrease the dosage of medicines for treatment.