What are the symptoms of bone metastasis in advanced lung cancer? Symptoms of bone metastasis in advanced lung cancer

When lung cancer develops to a certain extent, bone metastasis will occur. In severe cases, the patient will become paralyzed and lose the ability to take care of himself. In some cases, the patient may even lose his life. Therefore, we must actively treat lung cancer. Here is a brief introduction to the symptoms of bone metastasis in the late stage of lung cancer.

What are the symptoms of bone metastasis in advanced lung cancer?

Symptoms of lung cancer bone metastasis: bone-related changes

About 2.3% of patients have bone metastasis as the first symptom of lung cancer, and about 30%-40% of patients in the advanced stage will have bone metastasis. Many complications are also related to bone metastasis, such as severe bone pain, pathological fractures, hypercalcemia, and reduced behavioral ability. Studies have shown that 50% of patients with severe symptoms of lung cancer bone metastasis often have bone-related changes.

Symptoms of lung cancer bone metastasis: bone pain

Bone metastasis occurs due to hematogenous spread. High-incidence sites include the pelvis, ribs, vertebrae, and proximal long bones. Pain is the most common symptom of lung cancer bone metastasis. Periosteal inflammation and thickening are the root causes of pain. Bone metastasis usually occurs before bone pain occurs. 18.3% of patients with early non-small cell lung cancer develop bone metastasis, but only 27.2% develop bone pain, and most patients have no pain symptoms. Among patients with small cell lung cancer, 40% have positive bone scintigraphy at diagnosis, and bone metastasis is often diagnosed when there are no symptoms.

Symptoms of lung cancer bone metastasis: pathological fracture

In summary, the symptoms of lung cancer bone metastasis include: bone pain, pathological fractures. Primary lung cancer bone metastasis is usually osteolytic. Pathological fractures occur when bone strength is damaged, and the collapse and expansion of the vertebral body can cause spinal cord compression. Paraneoplastic syndrome without bone destruction and osteolytic bone metastasis may cause hypercalcemia, leading to disease exacerbation.

Experts say: When lung cancer develops to the late stage, it is very likely that cancer cells will spread throughout the body, and treatment at this time will be very difficult, so try to get treatment as soon as the disease is discovered. Because the early symptoms of lung cancer are not very obvious, it is recommended that you go to the hospital for regular check-ups to prevent them from happening.