Is ALT 70 serious? It needs to be taken seriously

Is ALT 70 serious? ALT 70U/L: First determine the normal reference value of ALT in your hospital, then determine the cause, in order to determine the severity of the disease.

What is the normal value of alanine aminotransferase ? Alanine aminotransferase is an enzyme involved in the body's protein metabolism. It can accelerate the conversion of protein amino acids in the body. It is widely present in the liver, kidneys, heart, muscles, and bones [1].
The reference value of normal serum alanine aminotransferase levels is not exactly the same because different hospitals use different testing methods. Some hospitals consider the reference value to be different for men and women, 9 to 51 U/L for men and 8 to 41 U/L for women[2]. Some hospitals consider the reference value to be 0 to 40 U/L; some hospitals even consider the reference value to be 3 to 30 U/L.
If the alanine aminotransferase is measured at 70U/L, it is necessary to know the normal reference value for the area in which you live in order to determine how many times the alanine aminotransferase of 70U/L exceeds the normal value.
Is an alanine aminotransferase of 70U/L serious ? According to the normal reference value of 3-30U/L, 70U/L is more than twice the upper limit of the normal value and needs to be taken seriously; if the patient is a male and the reference value for men in his hospital is 9-51U/L, 70U/L is a slight increase, and the clinical significance of the two is not the same.
It is generally believed that if the alanine aminotransferase is slightly elevated, the first thing to consider is whether it is caused by excessive drinking, excessive fatigue, strenuous exercise, or drug factors. In this case, after reasonable adjustments, the alanine aminotransferase will return to normal.
If the increase is obvious, it is considered to be caused by disease factors, which may indicate damage to organs such as the myocardium and liver. It is common in the following situations: hepatobiliary diseases, such as infectious hepatitis, liver cancer, active cirrhosis, toxic hepatitis, cholangitis and cholecystitis; cardiovascular diseases, such as myocardial infarction, myocarditis, liver congestion during heart failure, cerebral hemorrhage, etc.; skeletal muscle diseases, polymyositis, muscular dystrophy, etc., which can also increase alanine aminotransferase [3].
Therefore, when alanine aminotransferase is 70U/L, first determine the normal reference value, then determine the cause, and then determine the severity of the disease.
[1] Shi Jingsen, Wang Binghuang. Basic and Clinical Biliary Surgery, People's Medical Publishing House, October 2003.
[2] Duan Wenruo, Diagnosis and Individualized Treatment of Diabetes. People's Medical Publishing House. June 2010.
[3] Zhuang Junhua, Zhang Xiuming, Xu Ning. "Example of Medical Laboratory Quality System Documents". People's Medical Publishing House. March 2006.