Is bile duct cancer hereditary? No, it is not hereditary

Biliary duct cancer is not hereditary. The cause of bile duct cancer is still unclear, and there is no clear data showing that it is hereditary. It may be related to bile duct stones, congenital bile duct cysts, and biliary intestinal surgery. The specific causes are complicated.

1. Bile duct stones <br/>Bile duct stones can easily lead to intestinal obstruction and bile duct infection, which can cause chronic inflammation of the bile duct. Long-term stimulation of inflammation can cause malignant changes in the cells lining the bile duct.
2. Congenital bile duct cyst <br/>Especially extrahepatic congenital bile duct cyst is prone to canceration. Because the bile duct of patients with bile duct cyst is large, but the bile duct outlet is narrow, the bile flow is slow, bile duct stones occur, and cholangitis forms. Long-term bile duct inflammation may turn into cancer.
3. Biliary intestinal surgery <br/>Can destroy the normal anatomical relationship between the bile duct and the intestine, leading to loss of Qddi sphincter function. Long-term retention of intestinal contents can stimulate the bile duct epithelium and induce inflammation, stones, and cancer in the bile duct.