Cancer patients who have to undergo chemotherapy, doctors won’t tell you this!

All medicines are poisonous to some extent. Most anti-tumor drugs are highly toxic, and the therapeutic dose is close to the toxic dose. Therefore, we must consider the toxicity of the drugs before we can consider when to have chemotherapy based on our own situation and what the consequences will be. In fact, the various tests conducted at the beginning of the tumor diagnosis will have some impact on kidney function. In order to clarify the diagnosis and staging of the tumor and monitor the changes in tumor size during treatment, the patient needs to undergo imaging examinations, such as enhanced CT and angiography.

These examinations inevitably require the use of iodine-containing contrast agents, which may cause contrast-induced nephropathy in some cases. Then let's talk about the specific damage to the kidneys.

Prevent contrast-induced nephropathy and reduce the frequent use of large doses of contrast agents. If necessary, refill the intravenous saline. If the patient has a history of chronic renal insufficiency, diabetic nephropathy, multiple myeloma heart failure or other causes of reduced renal perfusion, large doses of contrast agents should be avoided and new contrast agents should be used as much as possible.

1. Phosphate drugs. Patients with tumors that have damage to renal function and bone metastases often need to be treated with phosphate drugs. On the one hand, phosphate drugs can relieve bone pain symptoms, and on the other hand, they can slow down the process of bone destruction.

A small number of patients treated with phosphate therapy will have increased urine protein. If more foam is found in the urine, a routine urine test should be performed. After the use of certain targeted therapeutic drugs, more foam will be found in the urine, and proteinuria will be detected in 10% to 25% of patients.

Precautions when using phosphate drugs: Phosphate drugs are used to treat bone metastasis of tumors and severe osteoporosis. The patient's serum creatinine level should be monitored during medication, and the injection time of phosphate should not be less than 4 hours. The phosphoric acid infusion time should be more than 15 minutes.

2 Chemotherapy drugs are the most common drugs that cause kidney damage and are also the most nephrotoxic drugs.

3. High-dose use of interleukin-1 in treatment with biological agents can lead to infiltration syndrome, insufficient blood circulation, reduced renal blood flow, and renal damage.

To sum up, no matter what medicine it is, we must understand our own situation in detail and what symptoms we will have so that we can take corresponding measures.