Several options for osteosarcoma treatment

Osteosarcoma mostly occurs in young people or children under 20 years old. Once they get this disease, it is a heavy blow to their family and children. In severe cases, amputation may be required or even life may end. Therefore, patients must first have the courage to accept the reality and actively cooperate with treatment. Now that medicine has advanced and there are many treatment methods, let me introduce several options for osteosarcoma treatment.

1. Radiofrequency local heating to treat osteosarcoma: Generally, radiofrequency heating is used during surgery, and the heating temperature can be controlled at 43-45% to ensure effective killing of osteosarcoma cells.

2. HIFU: Treatment with HIFU alone or combined with chemotherapy for osteosarcoma has shown that HIFU can inactivate the tumor in situ. Ultrasound follow-up results show that the bone tumor has shrunk and liquefaction necrosis foci have appeared in the treatment area.

3. Microwave high temperature treatment of osteosarcoma: By inserting a microwave antenna, the temperature of the tumor segment bone can be raised, and the surface temperature of the tumor can reach above 50°C and last for a considerable time of at least 30 minutes, thereby ensuring that all tumor cells are killed, while the surrounding normal tissues, especially the blood vessels and nerve bundles, are protected from high temperature damage due to protective measures such as local insulation and cooling. Clinical practice has proved that the microwave high temperature in situ inactivation technology for limb bone tumors has incomparable advantages over traditional limb preservation technology, that is, only the in situ separation of the tumor, including important blood vessels and nerve bundles and uninvaded muscles, is performed without destroying the internal and external structures of bones and joints.

4. Thermo-chemotherapy for osteosarcoma: Thermotherapy and chemotherapy drugs can exert synergistic anti-tumor effects. Thermotherapy promotes the entry of drugs into tumor cells and promotes drug-induced apoptosis of tumor cells. Drugs commonly used in tumor thermo-chemotherapy include: platinum, topoisomerase II inhibitors etoposide and teniplatin, topoisomerase I inhibitor camptothecin, hydroxycamptothecin and its derivatives, gemcitabine, paclitaxel, vinblastine, cyclophosphamide, mitomycin, etc.

The above are the treatment methods for osteosarcoma. I hope it will be helpful to you. I wish you good health!