What is the most serious case of osteosarcoma

If you have osteosarcoma, you must seek medical treatment as soon as possible. If you don't pay attention and treatment for a long time, osteosarcoma will spread rapidly, and in severe cases, it will endanger your life. Now we only need to understand some symptoms of osteosarcoma to help better detect and treat it in time to avoid causing too much harm to ourselves. Let me introduce what is the most serious case of osteosarcoma?

Osteosarcoma patients will experience the following symptoms, which can help patients detect and seek medical treatment in time.

1. Pain is an early symptom and may occur before the tumor appears. It is intermittent pain at first and gradually turns into continuous severe pain, especially at night.

2. Pain from large malignant tumors occurs earlier and more intensely, often with a history of local trauma. Tumors near the bone ends and joints are large, with varying hardness, tenderness, high local temperature, dilated veins, and sometimes palpable pulsations, and may be pathological fractures.

3. Overall health gradually declines to exhaustion, and most patients develop lung metastasis within one year.

4. There is often a history of local trauma. The tumor near the bone end near the joint is large, has varying hardness, and is tender.

5. The local temperature is high, the veins are dilated, and sometimes pulsation can be felt.

6. Clinically, symptoms of osteosarcoma often occur in adolescents, with fewer mandibular bones and more maxillary bones, and with a history of injury.

7. Intermittent numbness and pain occur in the affected area, which then turns into persistent severe pain accompanied by reflex pain.

8. The tumor grows rapidly, destroying the alveolar process and jawbone, causing loose teeth, displacement of teeth, and facial deformity.

9. Pathological fractures may also occur, which appear as irregular destruction on X-rays. Those that expand from the inside to the outside are osteolytic.

10. Bone cortex destruction is replaced by hyperplastic bone arranged in a solar radiation pattern, which is called osteoblastic type.

In addition to the above symptoms, the most serious situation will occur in the late stage of osteosarcoma. Metastasis in the late stage of osteosarcoma often leads to a significant increase in the concentration of calcium in the serum, resulting in calcium metabolism disorders, which is clinically known as hypercalcemia. In the early stage, patients may show fatigue, weakness, loss of appetite, nausea and vomiting, weight loss, confusion or coma, etc. In severe cases, hypercalcemia crisis may occur, which is often manifested as dehydration, high fever, heart rhythm disorder, heart and kidney failure or death. Zoledronic acid (Zometa) for injection can achieve satisfactory results in the treatment of hypercalcemia caused by bone cancer. Zometa is a new generation of bisphosphonates used to treat complications caused by bone metastasis or multiple myeloma-induced bone lesions. It can effectively treat benign and malignant bone lesions, such as osteoporosis, hypercalcemia caused by malignant tumors, and osteolytic bone metastasis. While actively treating the primary disease, you should also pay attention to a low-calcium diet and maintain a good mental outlook and psychological factors in order to achieve better results. Thereby avoiding the occurrence of complications in the late stage of bone cancer!

Once you find the symptoms of osteosarcoma, you should go to the hospital for treatment in time. If you can make a correct diagnosis in the early stage of the disease, we can choose scientific methods to treat sarcoma and choose scientific methods to deal with it. Because osteosarcoma, like other malignant tumors, is a serious health threat. Unlike other tumors, osteosarcoma is prone to occur in teenagers. It is the most common malignant, primary bone tumor, with high malignancy and rapid development. If it is not treated formally, the tumor will metastasize to the lungs within half a year to a year, leading to the death of the patient.