Is endometrial cancer likely to recur after 10 years?

Will endometrial cancer recur after 10 years? There are many ways to treat endometrial cancer, but surgery cannot completely eradicate cancer cells. After surgery, the body's anti-cancer ability decreases, making it easy for the cancer to recur and spread. So how long does it take for endometrial cancer to recur? The cause of the recurrence of endometrial cancer is still unknown, but its risk factors have long been noticed by people.

Experts say: "Obesity, diabetes, and high blood pressure are all related to endometrial cancer. Especially when these three conditions exist at the same time, the risk of endometrial cancer is higher than that of normal people. Therefore, obesity, diabetes, and high blood pressure are traditionally called the triad of endometrial cancer. Clinically, there are more fat patients and relatively fewer thin people, and this is closely related to the daily high-fat diet. Infertility patients, polycystic ovary syndrome patients, certain ovarian tumor patients, and family genetic tendencies are all high-risk groups for endometrial cancer." Family history, those with a family history of ovarian cancer, colon cancer, or breast cancer are more likely to develop endometrial cancer than those without a family history. Those with better economic conditions, especially those with a high-fat diet, are also high-risk groups for endometrial cancer. In the United States, some people have conducted a controlled study and found that the incidence of endometrial cancer in women with high cultural level and high economic income is significantly higher than that in women with low cultural level and low economic income. However, some people believe that it may be because the former are more likely to use estrogen replacement therapy for a long time and are obese. Generally speaking, the incidence of endometrial cancer is higher in economically developed countries than in underdeveloped countries, and higher in cities than in rural areas.

Obesity, hypertension and diabetes are generally called the endometrial cancer triad. In fact, hypertension and diabetes have no direct relationship with endometrial cancer. Obesity, hypertension and diabetes may be the consequences of hypothalamic-pituitary-adrenal dysfunction or metabolic abnormalities. At the same time, pituitary gonadotropin function may also be abnormal, resulting in anovulation and no progesterone secretion, causing the endometrium to be continuously stimulated by estrogen for a long time. Some people believe that premenopausal obesity, especially those who have been obese since a young age, is also a high-risk factor for endometrial cancer, because obese people are often accompanied by relative luteal phase progesterone deficiency, or at the same time accompanied by irregular menstruation or even amenorrhea.

Endometrial cancer can be divided into estrogen-dependent (type I) and estrogen-independent (type II) according to its pathogenesis and biological behavior. Most estrogen-dependent endometrial cancers are endometrioid carcinomas, and a small number are mucinous adenocarcinomas; estrogen-independent endometrial cancers include serous carcinomas, clear cell carcinomas, etc.

So, will endometrial cancer recur after 10 years? This question cannot be answered specifically. It depends on the patient's physical condition and whether their lifestyle is normal. There are many reasons for recurrence, and people need to understand them in time to better prevent them.