Early treatment of endometrial cancer

Early treatment of endometrial cancer

There are many ways to treat endometrial cancer. The impact of endometrial cancer is relatively large. After suffering from endometrial cancer, you will not be able to live and work normally. Therefore, you should pay attention to the treatment methods. The most common ones are surgical treatment, radiotherapy and hormone therapy. Let’s take a look at the introduction of specific treatment methods below.

1. Surgery is the first choice. Patients in stage I should undergo extrafascial total hysterectomy and bilateral adnexectomy, and patients in stage II should undergo extensive total hysterectomy and pelvic lymph node dissection.

2. Combined surgery and radiation therapy: For patients in stage I, if cancer cells are found in the ascites or the myometrium is infiltrated, and there is lymph node metastasis, external irradiation is given after surgery. For patients in stage II or some stage III, external irradiation or intracavitary irradiation is given before surgery, and surgery is performed 1 to 2 weeks after the end of radiotherapy.

3. Radiotherapy: The elderly, frail patients, patients with severe medical complications who cannot tolerate surgery, and patients in stage III or above who are not suitable for surgery can be treated with radiotherapy, including intracavitary and external irradiation.

4. Hormone therapy Young patients in the early stage who want to retain their fertility, patients with advanced cancer who cannot undergo surgery or with cancer recurrence can be treated with large doses of synthetic progesterone, such as 400 mg of medroxyprogesterone acetate, intramuscular injection, 2 to 3 times a week; 500 mg of progesterone acetate, intramuscular injection, 2 to 3 times a week, etc. The efficacy can be evaluated after at least 12 weeks.

5. The anti-estrogen drug tamoxifen has the same indications as progestin therapy. The general dose is 20-40 mg/d, taken orally. It can be used for a long time or in divided courses.

6. For advanced cases that cannot undergo surgery or radiotherapy, or those that relapse after treatment, anti-cancer chemotherapy can be combined with chemotherapy such as 5-fluorouracil (5-Fu), cyclophosphamide (CTX), mitomycin (MMC), doxorubicin (BDR), and cisplatin (DDP), which has a certain effect.

Women should choose the most suitable one according to the doctor's advice in their life. Everyone is afraid of suffering from endometrial cancer, but due to the lack of certain understanding of endometrial cancer, you must not procrastinate, otherwise it will get worse over time.

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