What does liver puncture biopsy mean

Liver puncture biopsy mainly involves biopsy of liver tissue. This method of examination is relatively damaging, and many patients are unwilling to undergo this examination. However, it has important guiding significance for the patient's liver condition. The accuracy of puncture biopsy can be as high as 80% or more. Of course, when conducting this examination, good care should be strengthened before and after the examination. Let's take a look at this aspect.

What does liver biopsy mean?

Liver biopsy is a biopsy of liver tissue. Liver puncture is very traumatic, which makes it difficult for many patients to accept it, and liver biopsy is not used as a routine examination in clinical practice. However, the accuracy rate of liver puncture biopsy is over 80%, which is currently a better examination method.

Clinical significance

Generally speaking, many patients with liver disease can be diagnosed through medical history inquiry and physical examination, or with necessary laboratory and imaging examinations. However, there are some diseases that cannot be clearly diagnosed and can only be concluded through liver puncture biopsy and pathological examination, such as lymphoma, liver cancer, tuberculosis, etc. There are also some diseases that are difficult to diagnose and require a liver biopsy combined with clinical symptoms to make a diagnosis, such as autoimmune hepatitis, chronic hepatitis, primary biliary cirrhosis, etc.

Many patients with chronic hepatitis B have been infected with HBV (hepatitis B virus) for a long time, but some of their transaminase results in blood tests are normal for a long time, some are repeatedly abnormal, and some are abnormal for only half a year. HBVDNA is positive or negative. For such patients, liver puncture examination can be used to find out whether the chronic hepatitis B is in the active stage and to infer the severity of the disease.

Liver puncture examination for hepatitis B patients is used as a standard for efficacy assessment. It is necessary to do a liver tissue examination, which is the most direct way to determine whether the hepatitis B patient has improved after treatment and the extent of recovery of the lesions. Because the lesions of hepatitis B are mainly in the liver, liver tissue examination is the most direct.

Indications

Liver diseases that cannot be clearly diagnosed through clinical, experimental or other auxiliary examinations include:

⒈ Abnormal liver function test, the nature of which is unknown. 2. Patients with normal liver function test but obvious symptoms and signs.

⒊ Unexplained hepatomegaly, portal hypertension or jaundice. 4. Diagnose the cause and type of viral hepatitis, track the condition, evaluate treatment results and determine the prognosis.

⒌Differential diagnosis of intrahepatic cholestasis.

⒍Grading of chronic hepatitis

Illustration of the liver

Illustration of the liver

⒎Differential diagnosis of chronic liver disease.

⒏ Cytological examination of intrahepatic tumors and drug treatment.

⒐ Make differential diagnosis for fever of unknown cause.

⒑ Diagnosis of diseases such as granulomatosis, tuberculosis, brucellosis, histiocytosis, coccidioidomycosis, and syphilis.