What are the targeted drugs for nasopharyngeal carcinoma

With the continuous development of society, there are more and more methods to treat tumors. Among them, targeted therapy is a better method to treat tumors in recent years, especially targeted therapy for nasopharyngeal carcinoma. Although targeted therapy for nasopharyngeal carcinoma is no longer news, there are still not many people who really know about targeted therapy for nasopharyngeal carcinoma. So, what are the targeted drugs for nasopharyngeal carcinoma?

Clinical research on targeted therapy for nasopharyngeal carcinoma

We probably don't know much about targeted therapy. Targeted therapy is a type of therapy that can inhibit the occurrence and development of tumors or eliminate tumors through various mechanisms. So what is the effect of targeted therapy for nasopharyngeal carcinoma? With the continuous improvement of medical standards, there are more and more ways to treat nasopharyngeal carcinoma, including: radiotherapy, surgical treatment, chemotherapy, immunotherapy and traditional Chinese medicine treatment. Radiotherapy is the first choice in clinical practice. Taixinsheng (Nimotuzumab) is a targeted drug for the treatment of nasopharyngeal carcinoma, and it is also the only targeted drug for the treatment of nasopharyngeal carcinoma in the world. It is the first autologous monoclonal antibody officially launched in China. Taixinsheng can significantly inhibit tumor cell proliferation, induce decomposition, promote cell apoptosis, inhibit tumor angiogenesis, and enhance the effect of radiotherapy and chemotherapy. The drug has strong targeting and low toxicity and side effects, representing the latest development direction in the field of tumor molecular targeted therapy.

Clinical application of targeted therapy for nasopharyngeal carcinoma

China is a high-incidence area for nasopharyngeal carcinoma. In recent years, comprehensive and individualized treatment for patients with advanced stage has become an important means to improve local control and survival rate. Molecular biological modification therapy has important clinical effects, which works by regulating cell biological activities and host immune response, including cytokines, monoclonal antibodies, immune effector cells, immunostimulants, gene drugs and non-cytotoxic small molecule target drugs.

The combined dual targeted therapy of Chinese and Western medicine solves several outstanding problems, so it is becoming more and more popular in clinical practice. In addition, combined with targeted therapy of traditional Chinese medicine, it can enhance the targeted effect, make the effect of targeted therapy more lasting and effective, and even achieve clinical recovery. Therefore, Chinese medicine treatment can be used throughout the entire process of cancer treatment.

Targeted therapy targets certain marker molecules overexpressed by tumor cells, selects specific blockers, and effectively interferes with the signal transduction pathways that are regulated by the marker molecules and are closely related to tumor occurrence, thereby inhibiting tumor growth, development and metastasis. Targeted therapy has achieved good results for some cancers such as breast cancer, but it is not suitable for all cancers. Targeted therapy for nasopharyngeal carcinoma is not commonly used, and radiotherapy is still the most commonly used, but there are also some targeted treatment plans for nasopharyngeal carcinoma in clinical practice.

Combining Chinese and Western medicine to treat nasopharyngeal carcinoma

Nasopharyngeal carcinoma is one of the common malignant tumors in China, and ranks first among head and neck malignant tumors. Due to various reasons, the incidence of nasopharyngeal carcinoma has shown an upward trend, with higher incidence in southern China, such as Guangdong, Guangxi, Hunan and other provinces, especially in the central and western parts of Guangdong, such as Zhaoqing, Foshan and Guangzhou. This is not a good thing for everyone. Because if nasopharyngeal carcinoma is not treated well, it will threaten life. When treating it, comprehensive treatment is usually the best. So how to carry out comprehensive treatment of nasopharyngeal carcinoma? Combining traditional Chinese and Western medicine to treat nasopharyngeal carcinoma is the right choice.

From the current status of nasopharyngeal carcinoma treatment research, combined chemotherapy is the main method at present, including adjuvant chemotherapy, neoadjuvant chemotherapy, synchronous chemoradiotherapy, molecular targeted therapy, etc. The indications of targeted treatment of nasopharyngeal carcinoma mainly include:

Some patients with advanced nasopharyngeal carcinoma (T3~4N0~1M0) and regionally advanced nasopharyngeal carcinoma (T1~2N2~3M0) should receive appropriate chemotherapy in addition to radiotherapy.

For patients with local advanced nasopharyngeal carcinoma (T3~4N2~3M0), their local recurrence rate and distant metastasis rate are quite high. Therefore, nasopharyngeal carcinoma must be combined with systemic treatment. The combination of Chinese and Western medicine has a certain effect in the treatment of nasopharyngeal carcinoma. Blood-activating and blood-stasis-removing drugs can improve microcirculation, increase blood flow, accelerate blood flow rate, and destroy the aggregation of fibrin around and inside tumor tissues, thereby improving the hypoxic tissue state.

Inhibitors for targeted therapy

Treatments for nasopharyngeal carcinoma include radiotherapy, chemotherapy, immunotherapy, and traditional Chinese medicine. Due to the particularity of the anatomical structure of the nasopharynx and the sensitivity of nasopharyngeal carcinoma tissue to radiation, radiotherapy is recognized as one of the primary treatments for nasopharyngeal carcinoma. In recent years, with the development of clinical high technology and the deepening of head and neck cancer cell and molecular biology research, biological treatments for nasopharyngeal carcinoma have also made great progress, as summarized below. In recent years, many anti-tumor targeted drugs for the treatment of nasopharyngeal carcinoma have been approved for marketing in the United States and Europe. These targeted drugs avoid the lack of specificity of traditional chemotherapy and radiotherapy, which brings about greater toxic and side effects, and have created a new era of connection between oncology diagnosis and treatment.

What are the targeted drugs for nasopharyngeal carcinoma? After the above introduction, I believe everyone has a relevant understanding of nasopharyngeal carcinoma. For nasopharyngeal carcinoma patients, it is very important to stay away from the harm of nasopharyngeal carcinoma. In addition, it is also necessary to develop good living habits and eating habits, actively exercise, enhance the body's resistance, and live a healthy life.