5 treatment considerations for prostate sarcoma

Prostatic sarcoma is a malignant tumor with a very fast progression. It often occurs in young people and children and has a very poor prognosis. Mastering its treatment principles is very important for improving survival rate.

(1) When prostatic sarcoma is confined to the prostatic capsule and has not yet infiltrated externally, radical cystoprostatectomy should be performed as soon as possible.

(2) When the tumor has only locally extended to the bladder or rectum and has not yet metastasized to distant sites, total pelvic organ resection can be performed. The indications should be strictly screened before surgery to avoid accelerated spread of tumor cells after extensive surgery.

(3) If patients with lymphosarcoma, leiomyosarcoma and reticulum cell sarcoma cannot undergo surgery, radiotherapy can be chosen. However, radiotherapy is not recommended for rhabdomyosarcoma.

(4) After a clear diagnosis, children can first receive preoperative chemotherapy, followed by cystectomy and urinary diversion surgery, and radiotherapy if there are residual cancer lesions. Alternatively, chemotherapy can be given first, followed by radiotherapy, and then bladder preservation surgery.

(5) Adult patients can receive preoperative chemotherapy, followed by prostate and pelvic radiotherapy, then radical cystoprostatectomy and pelvic lymph node dissection, and periodic chemotherapy after surgery.

Tips: Prostate sarcoma has a very poor prognosis

The prognosis of prostate sarcoma is extremely poor. From the onset of symptoms to death, the average time for children under 10 years old is 3 months, while for adults it is about 1 year. Rhabdomyosarcoma grows the fastest, and almost all patients die within 1 year; leiomyosarcoma and fibrosarcoma grow slowly, with an average survival of 2 to 3 years.