Experts tell you the causes of colorectal cancer

As one of the most common digestive tract malignancies, colorectal cancer is a malignant tumor originating from the colon mucosal epithelium. What are the causes of colorectal cancer ? Let's ask experts to tell you about the causes of colorectal cancer.

Like other malignant tumors, the cause of colorectal cancer is still unclear, but it may be related to the following factors.

1. Environmental factors. Studies have shown that among various environmental factors, diet is the most important factor in causing colorectal cancer. The incidence of colorectal cancer is positively correlated with the high fat consumption in food. In addition, it may also be related to the lack of trace elements and changes in living habits.

2. Genetic factors. There are reports of "family-based colorectal cancer" both at home and abroad. The number of blood relatives of colorectal cancer patients who died of the disease is significantly higher than that of the general population. Some colorectal adenomas, such as multiple familial adenomatosis, are autosomal dominant genetic diseases with a family prevalence rate of up to 50%. If not treated, colorectal cancer may occur after the age of 10. Recently, some scholars have studied the relationship between tumor suppressor genes and colorectal cancer and found that the susceptibility and pathogenesis of colorectal cancer are both related to genetic factors.

3. Colon adenoma: According to the research on autopsy materials from various places, the incidence of colon adenoma is quite consistent with that of colon cancer. According to statistics, the probability of colorectal cancer in patients with one adenoma is 5 times higher than that of patients without adenoma, and the probability of colorectal cancer in patients with multiple adenomas is 1 times higher than that of patients with a single adenoma.

4. Chronic colon inflammation. It is reported that the prevalence of intestinal cancer is positively correlated with the prevalence of schistosomiasis. It is generally believed that inflammatory changes in the intestine caused by schistosomiasis may lead to colon cancer. Other chronic inflammations of the intestine may also lead to cancer, such as ulcerative colitis, which has a 3% to 5% chance of canceration.

The above is an introduction to the causes of colorectal cancer. I believe everyone has a certain understanding of the causes of colorectal cancer. For more questions about the causes of colorectal cancer, you can consult our online experts.

For more information, please visit the colorectal cancer topic at http://www..com.cn/zhongliu/dca/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.