What are the main extrapulmonary symptoms of lung cancer?

The typical symptoms of lung cancer are cough, blood in sputum, chest pain, shortness of breath and other lung manifestations; however, according to statistics, about half of lung cancer patients initially show symptoms outside the lungs, and these symptoms often appear before the lungs, becoming an early sign of lung cancer. So what are the main extrapulmonary symptoms of lung cancer? Let's take a look at them together.

1. Osteoarthritis is the extrapulmonary symptom of pneumonia. This type of symptom is more common. Lung cancer cells can produce some special endocrine hormones (xenohormones), antigens and enzymes, which act on the bone and joint parts, causing swelling and pain in the bone and joints, often involving the tibia, fibula, ulna, radius and other bones and joints. The ends of the fingers and toes often swell and become clubbed, and X-ray examinations can show periosteal hyperplasia.

2. Shoulder and back pain is also an extrapulmonary symptom of pneumonia. Peripheral lung cancer often develops posteriorly and upwards, eroding the pleura, involving the ribs and chest wall tissue, thus causing shoulder and back pain. Such patients rarely have respiratory symptoms.

3. Hoarseness. Lung cancer metastasis compresses the laryngeal nerve, which can cause vocal cord paralysis and lead to hoarseness. Since lung cancer metastasis can appear in the early stage and sometimes grow faster than the primary lesion, the clinical manifestations of metastasis may appear before the primary lesion.

4. Neurological symptoms. Brain metastasis of lung cancer may cause headache, vomiting, sudden coma, aphasia, hemiplegia and other neurological symptoms. Because the lung symptoms are not obvious, they are often misdiagnosed as thrombosis or brain tumors.

5. Male breast enlargement is also a typical extrapulmonary symptom of pneumonia. About 10%-20% of male lung cancer patients have breast enlargement, some have unilateral enlargement, but most have bilateral enlargement. Moreover, this symptom appears about a year earlier than other lung symptoms such as cough, blood in sputum, chest pain, and shortness of breath. This is because some lung cancer cells can secrete chorionic gonadotropin, which can cause breast tissue hyperplasia and breast enlargement.

The above is an introduction to the extrapulmonary symptoms of pneumonia. I hope the above content can be helpful to you. If you find yourself with the above symptoms, you must pay attention to it and it is best to go to a regular hospital for examination.

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