What are the clinical manifestations of kidney cancer

Kidney cancer, also known as renal cell carcinoma and renal adenocarcinoma, originates from renal tubular epithelial cells and can occur in any part of the renal parenchyma, but is most common in the upper and lower parts, and a few cases can invade the entire kidney; the left and right kidneys have equal chances of developing the disease, and bilateral lesions account for 1% to 2%. For many years, hematuria, pain, and masses have been called the "triad" of renal cancer. So how much do you know about the clinical manifestations of renal cancer? Today, our experts will introduce it to you in detail.

1. Hematuria: Hematuria is often painless and intermittent. The whole process of hematuria is visible to the naked eye, and the interval shortens as the disease progresses. When renal cancer bleeds a lot, it may be accompanied by renal colic, which is often caused by blood clots passing through the ureter. The blood clots in renal cancer hematuria may form strips due to passing through the ureter. The degree of hematuria has nothing to do with the size of renal cancer. Renal cancer can sometimes manifest as persistent microscopic hematuria.

2. Lumbar pain: Lumbar pain is another common symptom of kidney cancer. Most of the time, it is dull pain, localized in the waist. The pain is often caused by the growth of the tumor and the swelling of the renal capsule. Blood clots passing through the ureter can also cause lumbago as mentioned above. When the tumor invades the surrounding organs and waist muscles, the pain is more severe and persistent.

3. Lumps: Lumps are also common symptoms. About 1/3 to 1/4 of kidney cancer patients can be found with enlarged kidneys when they seek medical treatment. The kidneys are relatively hidden, and lumps are difficult to detect before kidney cancer reaches a considerable size. Generally, a lump felt in the abdomen is a late-stage symptom.

4. Pain: Pain occurs in about 50% of cases and is also a late symptom. It is caused by the renal capsule or renal pelvis being involved by a gradually growing tumor, or by the tumor invading and compressing the connective tissue, muscles, lumbar vertebrae or lumbar nerves on the posterior abdominal wall, resulting in persistent pain in the affected side of the waist.

5. Other symptoms: fever of unknown cause, or metastasis when just discovered, fatigue, weight loss, loss of appetite, anemia, cough, hemoptysis and other lung symptoms. In addition, the effects of renal adenocarcinoma are caused by the endocrine activity of the tumor, including polycythemia, hypertension, hypotension, hypercalcemia, and fever syndrome. Although these systemic, toxic and endocrine effects are non-specific, about 30% of patients first have many mixed manifestations. Therefore, it is a valuable clue, and this finding is considered to be a systemic effect of the tumor.

The above is an introduction to the clinical manifestations of kidney cancer. I hope it will be helpful to you. If you have any symptoms of the disease, do not delay diagnosis and go to a regular hospital for treatment in time to avoid delaying the disease and causing serious consequences. If you have other questions, please consult our online experts for detailed answers.

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