What are the symptoms of advanced gallbladder cancer?

Gallbladder cancer is a very familiar disease term, but many people do not know much about it. Moreover, gallbladder cancer is difficult to diagnose in the early stages, and by the time it is discovered, it is too late. Therefore, I would like to introduce the symptoms of gallbladder cancer to you so that you can know them early and prevent the occurrence of gallbladder cancer.

The following are some of the most common symptoms of advanced gallbladder cancer;

1. Right upper abdominal pain

Most cases are persistent pain in the right upper abdomen, which may be aggravated paroxysmically and radiate to the right shoulder and waist and back. This symptom accounts for 84%. Since gallbladder cancer often coexists with gallbladder stones and inflammation, the pain is similar to that of calculous cholecystitis, starting with discomfort in the right upper abdomen, followed by persistent dull pain or dull pain, sometimes accompanied by paroxysmal severe pain and radiating to the right shoulder.

2. Skin itching

It may appear before or after the onset of jaundice, and may be accompanied by other symptoms such as tachycardia, bleeding tendency, mental depression, fatigue, steatorrhea, abdominal distension, etc. Skin itching is caused by the increase of bilirubin content in the blood, which soothes the peripheral nerves of the skin.

3. Jaundice

Due to the spread of cancer, about 1/3 to 1/2 of patients develop jaundice. Jaundice is the first symptom in a few patients, and most jaundice occurs after pain. Jaundice is persistent and progressively worsens. A few patients show intermittent jaundice. Jaundice often appears in the late stage of the disease, accounting for 36.5%, mostly due to cancer tissue invading the bile duct and causing malignant obstruction. It is also accompanied by weight loss, fatigue, and even cachexia, yellowing of the skin and mucous membranes, and difficult-to-treat skin itching.

Patients often have low or moderate fever, short-term weight loss, and anemia. When complicated by infection, it manifests as symptoms of acute cholecystitis and/or acute cholangitis. Complications include cholelithiasis and biliary infection, gastrointestinal bleeding and metastasis. Primary gallbladder cancer is prone to early metastasis, often infiltrating the liver and adjacent tissues, and can metastasize along the lymphatic system to the gallbladder lymph nodes and portal lymph nodes, etc. In the late stage, blood-borne spread often occurs.

We have a certain understanding of gallbladder cancer. We hope that friends can pay more attention to their physical condition in daily life. If there are any uncomfortable symptoms, it is necessary to seek timely treatment. If you have other questions, you can consult our online experts.

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