The main use of hyaluronic acid is to fill the skin, make it delicate and smooth, fight wrinkles, prevent rough skin, play a role in beauty and health care, and restore the physiological functions of the skin. It has a good regulating effect. However, you should also pay attention to whether you can smoke after injecting hyaluronic acid. This still depends on your personal physical condition. Because if there is an obvious needle mark after injecting hyaluronic acid, you should not smoke or drink coffee during this period. Main Application 1. It is a biochemical drug with high clinical value and is widely used in various ophthalmic surgeries, such as lens implantation, corneal transplantation and anti-glaucoma surgery. It can also be used to treat arthritis and speed up wound healing. Using it in cosmetics can play a unique role in protecting the skin, keeping the skin moisturized, smooth, delicate, tender and elastic, and has the effects of anti-wrinkle, anti-aging, beauty care and restoring the skin's physiological functions. 2//Uses: It can be used in cosmetic ointments, creams, honeys, milks, facial masks, shampoos and other products to maintain moisture in the skin and hair, moisturize the skin and hair, increase luster, and prevent skin cracking and wrinkles. Reference formula and preparation process of hyaluronic acid skin care cream: take 77 g of stearic acid and 10 g of liquid paraffin. 5 g, 35 g white vaseline, and 35 g glyceryl monostearate were mixed and heated to 80°C. 235 g water was taken and 0.01% sodium lauryl sulfate was added. 7 g and triethanolamine 2 . 45 g, heat to 80°C, and then add 10% paraben alcohol solution 3. 5 mL and 14 g of glycerol, slowly pour the oil phase into the water phase, stirring in the same direction while pouring, when the temperature drops to about 70℃, add 0. Pour 220 mL of 5% hyaluronic acid solution into the above solution, add a little essence, stir quickly until it becomes semi-solid and then package. 3. Treat arthritis and accelerate wound healing. Synthesis method The production process and technology of hyaluronic acid determine the difference in quality, so when using it, it must be a product produced from the correct source to have therapeutic effects. Generally speaking, there are three methods of extraction: 1. Animal tissue : The main raw materials are chicken combs and bovine vitreous body. The raw material is defatted and dehydrated with acetone or ethanol, soaked with distilled water, filtered, and then treated with sodium chloride aqueous solution and chloroform solution. Trypsin is then added and kept warm to obtain a mixed solution, which is finally treated with an ion exchanger and purified to obtain refined hyaluronic acid. The extraction rate of this method is extremely low, only about 1%, and the separation process is complicated, which makes hyaluronic acid expensive, up to US$5,000 per kilogram, limiting its large-scale use in cosmetics. 2. Microbial fermentation : using glucose as the carbon source in the fermentation liquid. Ferment in the culture medium for 48 hours. After the fermentation is completed, the mycelium and impurities are filtered out, and then a high-purity product is obtained by simple operations such as alcohol precipitation. The advantage of hyaluronic acid produced by the fermentation method is that the molecular weight can be set according to the product design. The key to the fermentation method lies in the selection of bacteria, with streptococci, lactococci, etc. being the most commonly used. |
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