Lymph node enlargement reactive hyperplasia

Lymph is a very common thing in human body structure. It promotes people's immunity, but there is also the possibility of lymph mutation, which may mutate into lymphoma or other conditions. This was in the early days when people were more concerned about the lymph in their bodies, and some people would suffer from problems such as swollen and reactive hyperplasia of the lymph nodes. This is a relatively common lymphatic problem. There are many types, each of which has a certain impact on people's physical health. Below is an analysis of the causes of lymph node enlargement and hyperplasia.

1. Types of reactive lymph node hyperplasia

There are many types of reactive lymph node hyperplasia, which can be divided into the following types: nonspecific reactive lymph follicular hyperplasia, giant lymph node hyperplasia, and angioimmunoblastic lymphadenopathy.

The prognosis of this disease varies greatly. About half of the patients can survive 2 to 4 years without any treatment, and about 25% can be relieved with hormone therapy or other chemotherapy drugs. Some lesions are progressive and may develop into malignant lymphoma, which has a poor prognosis. In the late stages, due to low immunity, most patients die from secondary infections.

2. What to do if lymph node enlargement and reactive hyperplasia occur

This situation is caused by inflammatory response stimulation, and this symptom may be discovered after examination. In this case, we can take some oral medications, such as cephalexin capsules, ciprofloxacin tablets, etc., to eliminate inflammation, and then observe and see.

3. What is nonspecific reactive lymphofollicular hyperplasia?

The main features of nonspecific reactive lymphofollicular hyperplasia are lymphadenopathy, lymphofollicular hyperplasia, and marked enlargement of germinal centers. The number of lymphoid follicles increases, and they are not only distributed in the lymph node cortex, but also scattered at the cortical-medullary junction and in the medulla. The follicles vary in size and shape, with clear boundaries.

The germinal center is significantly enlarged and proliferated, containing many transformed lymphocytes of various types, with large nuclei, with or without cleavage, and frequent nuclear division images. There are also many phagocytes, and the cytoplasm contains phagocytosed cell debris. The germinal centers are surrounded by small lymphocytes. Infiltration of plasma cells, histiocytes, and a small number of neutrophils and eosinophils can be seen in the lymphoid tissue between the follicles. Reticular cell and endothelial cell proliferation in the lymphatic sinuses.