Symptoms of periosteal hyperplasia

Everyone has heard of bone hyperplasia, but not everyone has heard of periosteal hyperplasia. This condition is different from the ordinary one. In current clinical practice, it mainly manifests as pain, local swelling, and even damage to the eardrum and bone. In addition, there is often pain and a feeling of wear and tear when walking. This is a problem that deserves attention.

Periosteal hyperplasia-Concept

Also known as periosteal reaction, it refers to the periosteal new bone formation produced by increased activity of osteoblasts in the inner layer of the periosteum under pathological conditions. A periosteal reaction generally means that there is destruction or damage to the bone. Histologically, it can be seen that the number of osteoblasts in the inner layer of the periosteum increases, forming new bone trabeculae. Because the plaster has a high consistency, it has a series of advantages such as high content of effective ingredients, slow precipitation rate, long-lasting effect, and effective local efficacy. For periosteal hyperplasia, Wuzhi must be applied externally. The effective ingredients can penetrate into the skin to produce effects such as promoting blood circulation, relieving pain, removing blood stasis, dredge meridians and collaterals, opening up the orifices and penetrating the bones, and dispelling wind and cold.

Periosteal hyperplasia-mechanism

The fibrous layer of the outer layer of the periosteum is formed by the transformation of surrounding soft tissues such as fascia, fat, and muscle. The fibroblasts in the fibrous layer are transformed into osteoprogenitor cells through enlargement of the nucleus and increase of cytoplasm. The nucleus of the osteoprogenitor cells further enlarges and is accompanied by mitosis, thus forming a cell formation layer in which cells with the ability to secrete bone matrix appear.

Periosteal thickening occurs before the formation of new periosteal bone. During the continuous formation of new periosteal bone, thickened periosteum is always seen covering the surface of new periosteal bone. Therefore, periosteal thickening is both an early periosteal abnormality before the formation of periosteal new bone and a necessary preparation for the continuous formation of periosteal new bone.