Inheritance of pituitary microadenoma

Pituitary microadenoma is not too serious in clinical practice, but it is not a simple disease either. This disease can be combined with multiple types of treatment, and the symptoms shown by each person are different, so patients should pay attention to have a one-sided understanding of the disease first, and judge it based on the symptoms, examination and related quality of the disease.

Overview

Clinically, pituitary tumors with a diameter of ≤10 mm are called pituitary microadenomas, and the diagnosis is mostly confirmed by imaging (CT or MRI) (pituitary tumors with a diameter of >10 mm are called pituitary macroadenomas). Some pituitary microadenomas are discovered accidentally during head CT or MRI examinations for other reasons. The patients have no clinical symptoms of pituitary tumors, and pituitary endocrinology examinations are completely normal. There is no need to take any treatment measures for such patients, and regular follow-up is sufficient. If there are no symptoms, follow-up with enhanced MRI of the head should be performed every 1 to 2 years.

Clinical manifestations

The patient's clinical manifestations combined with pituitary endocrinology and pituitary imaging examinations can usually determine the type of pituitary microadenoma, such as prolactin microadenoma, GH microadenoma, ACTH microadenoma, or microadenoma with no obvious effect on secretory function (only headache, or mild menstrual disorders in young women).

treat

Radiation therapy. Radiotherapy can be chosen for patients with contraindications to surgery or patients with residual tumors after surgery. Radiotherapy is relatively effective for GH microadenomas, and 60%~90% of GH adenomas are sensitive to radiotherapy. Most patients achieve significant results in about 2 years, but up to 40% of patients suffer from hypopituitarism after radiotherapy. It is contraindicated in patients with visual field defects and intracranial hypertension.

The treatment of pituitary microadenomas requires high precision because of the special environment within the brain and the complex blood vessels and nerves. Therefore, no matter what treatment is used, high precision is required. Another characteristic of pituitary tumors is that they grow in irregular shapes, which poses a great challenge to treatment. In this case, surgical treatment cannot completely remove the tumor. If it is not completely removed, it will recur. Moreover, surgery brings great harm to patients, especially the treatment of intracranial tumors, which requires craniotomy and may affect future life.

There is no need to worry about the above when using CyberKnife to treat pituitary microadenomas. First of all, the accuracy of CyberKnife treatment is very high, and the error does not exceed 0.5mm, so there is no need to consider the issue of accuracy. As the most advanced equipment for radiotherapy, CyberKnife naturally has the best accuracy. CyberKnife treatment does not require craniotomy and will not cause any trauma. The recovery time after treatment is also relatively short, and the effect is significant without affecting the patient's normal life.