Inheritance of light rash

Light rash is a very obvious disease. It is enough to cause great damage to the patient's skin, and may even cause erythema and dermatitis. It will begin to spread significantly after exposure to sunlight, and may even be accompanied by edema. Whether light rash is hereditary depends on the onset cycle and regularity of the disease, as well as the individual's genetic chain.

Pathological etiology

The cause of the disease is not very clear, but genetics and geographical environment may be important pathogenic factors. Most people believe that it is a delayed hypersensitivity reaction caused by sunlight sensitization. This disease is an immune sensitization of skin antigens caused by changes in ultraviolet radiation. Its pathogenic spectrum is mainly medium-wave ultraviolet rays. The sun exposure process and the amount of radiation received vary greatly among different patients. Some patients have a family history of photosensitivity.

Disease diagnosis

Based on the history of disease, the season of high incidence, the chronic course, and the abnormal reaction of the ultraviolet erythema reaction test, it is not difficult to diagnose. This disease needs to be differentiated from the following diseases:

1. The occurrence of eczema lesions has nothing to do with radiation or season.

2. Erythema multiforme lesions are more common on the hands and feet. They are easier to distinguish if there is typical iridophore erythema. The onset of the disease is not related to light exposure.

3. The rash of lupus erythematosus is a persistent erythema with keratotic scales on the surface, enlarged hair follicle openings, as well as atrophic scars and dilated capillaries.

4. The papules of neurodermatitis are flat and consistent with the skin texture. They are not related to light exposure and are not affected by seasons.

Inspection method

Pathological examination showed dermal papillary edema, which was pale purple, and dense lymphocyte infiltration around the superficial and deep blood vessels in the dermis. In some cases, the epidermis changed into spongioedema, blisters in the epidermis and individual necrotic keratinocytes. In some cases, there was only fire around the superficial or deep blood vessels in the dermis without obvious papillary edema.

complication

This disease has no special complications.