What is the medicine for anti-inflammatory injection

Many times, if we have a wound or inflammation in our body, we need to get an IV drip to reduce the inflammation. Many of my friends actually don’t know what the anti-inflammatory drugs used for intravenous drips are. In fact, this is mainly due to the different types of anti-inflammatory drugs selected based on the different types of inflammation. If you are curious about this issue, you can actually consult a doctor, and it can also help avoid some allergic reactions.

Intravenous injection is just one way for drugs to enter the human blood circulation. Oral drugs need to be absorbed by the gastrointestinal tract before entering the blood circulation, and they take a slow effect, so they are suitable for mild diseases. Intramuscular injection also absorbs drugs into the blood through muscle blood vessels, which is faster than oral administration, but the dosage is limited, so it is suitable for more serious diseases. Infusion can directly inject larger amounts of medicine into blood vessels and distribute them to diseased tissues and organs through the blood circulation. It has the fastest onset of effect and is suitable for serious diseases. Medication needs to be used according to the needs of the disease. The administration of anti-inflammatory and bactericidal drugs will produce an anti-inflammatory effect.

Simply put, after the drug enters the body and is absorbed, it is transported to various tissues and organs through the systemic circulation. At the same time, it is metabolized in different parts of the body. The active substances metabolized will take effect after reaching an appropriate concentration at the site of inflammation. Finally, the metabolites and inactivated drugs are excreted from the body.

Taking oral roxithromycin as an example, roxithromycin is swallowed through the mouth, passes through the gastrointestinal tract, and is absorbed by the intestinal capillaries in the small intestine wall. It flows with the blood to the superior and inferior mesenteric veins, and then enters the liver through the portal vein. In the liver, part of the roxithromycin can be metabolized and inactivated, reducing the amount of the drug entering the human circulation. This is medically known as the "first-pass effect". Most of the roxithromycin that successfully escapes from the liver enters the blood circulation from the liver. In the blood, some of the roxithromycin is bound by proteins in the blood. After binding, the roxithromycin cannot play a role. Only the unbound ones can leave the blood and enter the tissues to show their strength. But there is no need to worry about the roxithromycin being retained by proteins all the time. When the unbound drugs in the blood are transferred to the tissues and the concentration of unbound drugs decreases, the bound roxithromycin becomes free again, and then the free roxithromycin is distributed to various tissues of the body with the blood. Roxithromycin also has its own personality. It likes to stay in the tonsils, sinuses, middle ears, lungs, prostate and other urogenital tract tissues. Therefore, these tissues slowly reach effective therapeutic concentrations. When these tissues are disturbed by bacteria and become inflamed, the roxithromycin begins to play an antibacterial role, which is what people mistakenly understand as anti-inflammatory.

Anti-inflammatory drugs are not targeted at organs or diseases, but at bacteria. Whether taken orally or injected, they will enter the human blood circulation system and be transported to organs throughout the body through the blood. All organs have blood supply (except dead cells). When the anti-inflammatory drug reaches a certain concentration in the blood, as long as there are bacteria in the organs that can be killed by the anti-inflammatory drug, the bacteria will be eliminated. This is the so-called one-size-fits-all approach. If a person has two organs infected by the same bacteria at the same time, anti-inflammatory drugs can treat the infections in both organs at the same time. Why do some people have diarrhea after taking anti-inflammatory drugs? Because the beneficial bacteria in the intestines are also killed, leading to dysbacteriosis in the body. One of the manifestations of dysbacteriosis is diarrhea.

To sum up, first, the route of administration of anti-inflammatory drugs is that they can be distributed throughout the body, that is, they can enter the blood circulation in large quantities. For example, if it is eye drops, don't expect it to be able to treat urinary tract infections at the same time. Second, anti-inflammatory drugs enter the human body's organs throughout the body through the blood. When the anti-inflammatory drugs reach a certain concentration, except for some special cases, such as the eyes and ears, the blood flow is not large and the anti-inflammatory drugs cannot enter, and the same effect cannot be achieved. Third, the bacteria that infect the organs are not resistant to this anti-inflammatory drug.