How to treat mild nephritis

If you find that you have mild nephritis after examination, you need to seek timely treatment. This disease should never be ignored even if there are no symptoms at the beginning, because the treatment of this disease is still very troublesome. Many people will experience recurrence of symptoms after a few years of treatment. This is because daily care is not done well, so patients must avoid putting their bodies in a state of fatigue.

1. General treatment

This includes avoiding fatigue, eliminating triggers such as infection, avoiding contact with nephrotoxic drugs or poisons, adopting a healthy lifestyle (such as quitting smoking, exercising moderately, and controlling emotions), and a reasonable diet. During the acute phase, you should rest in bed and gradually increase your activity after the clinical symptoms improve. A low-salt diet (less than 3g per day) should be given during the acute phase. People with normal renal function do not need to limit protein intake, but in cases of azotemia, protein intake should be limited, and high-quality animal protein should be the main source. People with oliguria should limit their fluid intake.

2. Treatment targeting the cause and pathogenesis

Treatment targeting the immune pathogenesis often includes glucocorticoids and immunosuppressants. Blood purification treatments such as plasma exchange and immunoadsorption can effectively remove autoantibodies and antigen-antibody complexes from the body. Treatment targeting non-immune pathogenesis, including hypertension, hyperlipidemia, hyperglycemia, hyperuricemia, obesity, proteinuria, intrarenal hypercoagulable state, renin-angiotensin system activation, and oxidative stress. Renin-angiotensin system blockers, such as ACEI/ARB, are one of the most important therapeutic measures to slow the progression of kidney disease.

3. Treatment of comorbidities and complications

Patients with kidney disease often have multiple comorbidities, such as metabolic abnormalities, hypertension, coronary heart disease, heart failure and cirrhosis, which may aggravate the progression of kidney disease and should be actively treated.

Complications of kidney disease may involve various systems, such as infection, abnormal coagulation function, renal hypertension, renal anemia, renal osteodystrophy, water, electrolyte and acid-base imbalance, acute left heart failure, pulmonary edema and uremic encephalopathy, and should be treated actively.

4. Renal replacement therapy

Including dialysis treatment and kidney transplantation. When acute or chronic renal failure occurs and dialysis is indicated, dialysis treatment should be given promptly. There are two types of dialysis treatment: peritoneal dialysis and hemodialysis.