What does atypical glandular cells mean

Atypical glandular cells are a type of cell that lives in the female uterus. If a woman suffers from gynecological diseases, such as cervicitis, vaginitis, etc., these inflammations will cause lesions in the atypical glandular cells, thereby awakening other diseases hidden in the female body. Therefore, when a woman has a gynecological disease, she must go to the hospital for treatment in time. So, what do atypical glandular cells mean? Let me introduce it to you below.

According to its cytopathological morphology, AGC can be divided into:

(1) atypical glandular cells of unknown significance (AGC-NOS);

(2) Atypical glandular cells, prone to intraepithelial neoplasia (cervical glandular[1]ar intraepithelial neoplasm, abbreviated as CGIN);

(3) Atypical glandular cells, which tend to be endocervical adenocarinoma in situ (AIS);

(4) Atypical glandular cells, the origin cannot be determined.

Atypical squamous cells are caused by cervical inflammation, which leads to cell mutation. Doctors will usually repeat the smear test after a few months to determine the cause.

Patients with atypical squamous cells have cervical squamous cell lesions (Squamous Intraepithelial Leison, referred to as SIL), which can cause cell mutations. Milder lesions indicate that the patient has been infected with human papillomavirus or has low-grade cervical intraepithelial neoplasia (CIN). The chance of this type of condition developing into cervical cancer is less than 1%. More severe lesions indicate that the patient has a high degree of cervical intraepithelial neoplasia (CIN), and the risk of developing cervical cancer may be as high as 5%. Cervical intraepithelial neoplasia (CIN) is an abnormal lesion in the cells on the surface of the cervix, which is a precancerous change. CIN can be divided into three grades: CIN Ⅰ - only one-third of the thickness of the cervical epithelium has mutant cells. CINⅡ--Abnormal cells appear in only two-thirds of the thickness of the cervical epithelium. CINⅢ--Abnormal cells appear in the entire layer of cervical epithelium. Since the mutation is limited to the most superficial cell layer and has not invaded deeper tissues, even CINⅢ is not cancer. Who needs to be tested?

Women who have ever had sexual intercourse should have regular cervical smear tests starting at age 25. If the results of the first examination are normal, another examination should be performed one year later. If the second examination result is also normal, an examination can be carried out every three years. If you have regular checkups and the results are normal each time, you can stop after the age of 65. Otherwise, you should continue to have regular checkups. If any abnormality is found during the examination, the doctor will follow up and suggest increasing the frequency of examinations. Women who undergo smear tests every year or every other year can reduce the incidence of cervical cancer by 93%; every three years, it can reduce the incidence by 91%; every five years, it can reduce the incidence by 84%; every ten years, it can reduce the incidence by 64%. In summary, early stage cervical cancer may be asymptomatic and can only be detected through regular cervical screening. However, some patients with cervical cancer may also experience the following symptoms: abnormal or irregular vaginal bleeding, bleeding between periods or after sexual intercourse, bleeding after menstruation or bloody discharge. Regardless of the amount or color of the bleeding, you should see a doctor for a check-up. Later symptoms include back pain, swollen feet, and difficulty urinating or defecating. During clinical examination, doctors may find enlarged lymph nodes in the patient's groin or neck, and an abnormal passage between the vagina and rectum. In conclusion, regular check-ups can easily detect early cell changes, which helps in early follow-up and treatment, thus increasing the chances of treatment.