The difference between erythromycin cyclohexetine and cephalosporin

Both erythromycin cyclic ester and cephalexin are very common drugs in daily life. Since they are similar in some places, people tend to confuse the two. In fact, as long as you study it carefully, you will find that there are many differences between erythromycin cyclic esters and cephalosporin in terms of indications and adverse reactions. Friends in need can learn more about the relevant knowledge to better play their roles.

1. Erythromycin

Indications

Infections caused by sensitive bacteria, such as tonsillitis, pharyngitis, bacterial pneumonia, mycoplasma pneumonia, stomatitis, Legionnaires' disease, diphtheria, whooping cough, scarlet fever, erythrasma, erysipelas, gonorrhea, early syphilis, chancroid, urethritis, Campylobacter enteritis, amoebic enteritis, etc.

Adverse Reactions

Cyclohexetine is well tolerated, but the following adverse reactions are occasionally seen:

1. Gastrointestinal dysfunction: such as nausea, vomiting, and diarrhea.

2. Allergic reactions: such as rash, eosinophilia, and fever.

3. Reversible hearing loss.

4. Long-term and repeated use may cause overgrowth of insensitive bacteria (such as Clostridium difficile) and fungi.

Drug interactions

Taking erythromycin cyclopentyl with the following drugs at the same time may cause drug interactions.

1. Theophylline: The serum concentration and toxicity of theophylline will increase. Patients receiving treatment with this product should reduce the dosage of theophylline.

2. Digoxin: The serum concentration and absorption of digoxin will increase.

3. Cyclosporine A: The serum concentration and renal toxicity of cyclosporine A will increase.

4. Coumarin anticoagulants: The effects of this type of drugs will increase.

5. Cyclohexetine will produce antagonistic effects when used in combination with lincomycin or clindamycin.

(ii) Cephalosporins

Cephalosporins are a class of antibiotics that are obtained by semi-synthetically modifying the side chains of natural cephalosporin C obtained by culturing Cephalosporin C as raw materials. There are about 30 commonly used species, which are divided into one, two, three and four generations according to the time of their invention and their antibacterial properties. Do not use before or after drinking alcohol. Shock and fainting are very likely to occur, and the elderly may even be in danger of death. In the antibiotic market, cephalosporin antibiotics occupy a large share, and their related intermediates also show considerable market potential. The best-selling varieties of cephalosporin antibiotics include ceftriaxone sodium, cefazolin sodium, cefotaxime, ceftriaxone, cefoperazone and cefuroxime (ester), and the corresponding intermediates include 7-ACA, 7-ADCA, GCLE, aminothiocarbamic acid, AE-active ester, triazine ring, tetrazolylacetic acid, methylthiotetrazolium, HO-EPCP, methoxyamine hydrochloride, furanamine salt (SIMA) and chlorosulfonic acid isocyanate, etc.

Function: It is mainly used clinically for pneumonia, bronchitis, peritonitis, pleurisy caused by sensitive bacteria, as well as infections of the skin and soft tissues, urinary tract, bile duct bones and joints, facial features, etc. It is also used for sepsis and meningitis.

Note: It is forbidden for people with allergies to use this product. Use of this product by teenagers and children may occasionally cause gallstones, but the condition will disappear after stopping the drug.