What causes urinary occult blood disease

What causes urinary occult blood disease

Many people do not know much about urinary occult blood disease. Urinary occult blood disease is a common disease in urology. The main causes of this phenomenon include kidney disease, urinary tract infection, and systemic diseases. Therefore, if urine occult blood is found to be positive through routine urine examination, we must first be alert to kidney disease. Urinary occult blood disease can also be easily confused with some symptoms, such as urine protein and urine sugar.

There are many causes of occult blood in urine, which can be temporary or persistent. Temporary occult blood in the urine may occur after strenuous exercise, excessive mental stress, or dehydration. This condition will generally disappear on its own after a day or two and is not a serious problem. However, persistent occult blood in urine is more serious. Upper respiratory tract infection, febrile diseases, nephritis, tumors, stones, tuberculosis and urinary tract infections can cause occult blood in urine. At this time, we should attach great importance to it, make further diagnosis to determine the condition, and provide timely diagnosis and treatment.

What should I do if urine occult blood is positive?

After the test results come out, occult blood bothers some people. In addition to objective factors such as exercise-induced hematuria and drug-induced hematuria, we should also conduct relevant examinations to confirm the diagnosis. When urinary tract infection, stones, tumors and other factors are excluded, the possibility of kidney disease should be considered. At this time, you should go to the hospital as soon as possible. Many patients with occult blood in urine neglect treatment in the early stages, thus delaying the disease.

In kidney diseases, such as acute and chronic nephritis, pyelonephritis, etc., hematuria will occur. When various pathological damages lead to local microcirculation disorders in the damaged kidney, renal tissue will be ischemic and hypoxic, thereby releasing inflammatory mediators and initiating the process of renal fibrosis. At this time, local pathological changes will occur in the glomeruli: mesangial cell proliferation, increased mesangial matrix, changes in the glomerular basement membrane, leading to charge barrier damage and increased renal permeability, resulting in urinary occult blood and proteinuria.

With the leakage of hematuria and proteinuria, kidney damage is further aggravated, and the glomeruli gradually progress to the stage of fibrosis and sclerosis. Clinically, systematic and targeted treatment should be adopted to promptly block the process of renal fibrosis and avoid renal failure caused by the gradual reduction of functional renal units.

Currently, there are mainly the following ways to treat occult blood in urine:

① Conventional medication, if it can reduce inflammation, then reduce inflammation. If it cannot, eliminate urine protein first;

② Unless macroscopic hematuria occurs, do not give overly aggressive treatment.

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